MYC and gastric adenocarcinoma carcinogenesis

Show simple item record Calcagno, Danielle Queiroz Leal, Mariana Ferreira [UNIFESP] Assumpcao, Paulo Pimentel Smith, Marilia de Arruda Cardoso [UNIFESP] Burbano, Rommel Rodriguez 2016-01-24T13:51:46Z 2016-01-24T13:51:46Z 2008-10-21
dc.identifier.citation World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 14, n. 39, p. 5962-5968, 2008.
dc.identifier.issn 1007-9327
dc.description.abstract MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been described as a key element of several carcinogenesis processes in humans. Many studies have shown an association between MYC deregulation and gastric cancer. MYC deregulation is also seen in gastric preneoplastic lesions and thus it may have a role in early gastric carcinogenesis. Several studies have suggested that amplification is the main mechanism of MYC deregulation in gastric cancer. in the present review, we focus on the deregulation of the MYC oncogene in gastric adenocarcinorna carcinogenesis, including its association with Helicobacterpylori (Hpylorl) and clinical applications. (c) 2008 the WIG Press. All rights reserved. en
dc.description.sponsorship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 5962-5968
dc.language.iso eng
dc.publisher Baishideng Publ Grp Co Ltd
dc.relation.ispartof World Journal of Gastroenterology
dc.rights Acesso aberto
dc.subject MYC en
dc.subject Gastric adenocarcinoma en
dc.subject Gastric preneoplastic lesions en
dc.subject Gastric carcinogenesis en
dc.subject Helicobacter pylori en
dc.title MYC and gastric adenocarcinoma carcinogenesis en
dc.type Resenha
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Fed Univ Para
dc.description.affiliation Universidade Federal de São Paulo, Dept Morphol & Genet, Div Genet, BR-04023900 São Paulo, Brazil
dc.description.affiliation Fed Univ Para, Joao de Barros Barreto Univ Hosp, BR-66073000 Belem, Para, Brazil
dc.description.affiliation Fed Univ Para, Dept Biol, Lab Citogenet Humana, Inst Ciencias Biol, BR-66075900 Belem, Para, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Morphol & Genet, Div Genet, BR-04023900 São Paulo, Brazil
dc.identifier.doi 10.3748/wjg.14.5962
dc.description.source Web of Science
dc.identifier.wos WOS:000260384100002


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