Prevalence and risk factors of metabolic syndrome in Brazilian and Italian obese adolescents: a comparison study

Prevalence and risk factors of metabolic syndrome in Brazilian and Italian obese adolescents: a comparison study

Autor Caranti, D. A. Autor UNIFESP Google Scholar
Lazzer, S. Google Scholar
Damaso, A. R. Autor UNIFESP Google Scholar
Agosti, F. Google Scholar
Zennaro, R. Google Scholar
Mello, M. T. de Autor UNIFESP Google Scholar
Tufik, S. Autor UNIFESP Google Scholar
Sartorio, A. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Univ Udine
IRCCS
Resumo Background: Metabolic syndrome (MS) prevalence between different populations in obese adolescents is scanty to date. Objective: To compare the MS prevalence and related risk factors in Brazilian and Italian obese adolescents. Methods: A total of 509 adolescents (110 Brazilian, 399 Italian), aged 15-19 years. Anthropometric characteristics, triglycerides (TG), total, low-density lipoprotein (LDL)-, high-density lipoprotein (HDL)-cholesterol, fasting plasma glucose (FPG), insulin, homeostasis model assessment of insulin resistance (HOMA-IR) and blood pressure were measured. Results: Age, body mass index (BMI) and BMI z-score were not significantly different between the two subgroups. BMI z-score, TG, FPG, HOMA-IR and systolic blood pressure (SBP) were significantly higher in boys than in girls both in Brazilian and Italian adolescents, while HDL-cholesterol levels were lower in boys than in girls. No significant differences were observed in BMI, LDL and total-cholesterol and DBP in two genders and groups. Insulin, FPG, HOMA-IR and TG were significantly higher, while LDL-cholesterol and SBP were significantly lower in Brazilian than in Italian subjects, both in males and females. HDL and total-cholesterol and diastolic blood pressure (DBP) were not significantly different between the two subgroups and genders. MS prevalence was higher in Brazilian than in Italian obese boys (34.8 vs. 23.6%, p < 0.001) and girls (15.6 vs. 12.5%, p < 0.01). the most frequently altered parameter was HOMA-IR both in subjects with MS (100% in Brazilian and 81.8% in Italian) and without MS (42.9% and 11.7%). Conclusion: Metabolic syndrome represents a worldwide emerging health problem in different ethnical populations, the alterations of the risk factors related to MS (different in their prevalence between different subgroups) being strictly linked to the degree of obesity.
Idioma Inglês
Financiador Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
AFIP
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
CENESP
FADA
UNIFESP
Progetti di Ricerca Corrente, Italian Institute for Auxology, Milan
Número do financiamento 9814303-3
2006# 00684-3A
Data de publicação 2008-10-01
Publicado em International Journal of Clinical Practice. Malden: Wiley-Blackwell, v. 62, n. 10, p. 1526-1532, 2008.
ISSN 1368-5031 (Sherpa/Romeo, fator de impacto)
Publicador Wiley-Blackwell
Extensão 1526-1532
Fonte http://dx.doi.org/10.1111/j.1742-1241.2008.01826.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000259025500012
Endereço permanente http://repositorio.unifesp.br/handle/11600/30963

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