Deep anterior lamellar transplant using lyophilized and optisol corneas in patients with keratoconus

Deep anterior lamellar transplant using lyophilized and optisol corneas in patients with keratoconus

Autor Farias, Roberta Autor UNIFESP Google Scholar
Barbosa, Luciene Autor UNIFESP Google Scholar
Lima, Acacio Google Scholar
Mayumi, Eliane Google Scholar
Lourenco, Andrea Google Scholar
Freitas, Denise de Autor UNIFESP Google Scholar
Allemann, Norma Google Scholar
Vieira, Luis Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Sorocaba Eye Bank
Resumo Purpose: Prospective randomized clinical trial to evaluate the efficacy of lyophilized corneas for deep anterior lamellar keratoplasty (DALK) in patients with keratoconus.Methods: Ten eyes underwent DALK and received corneas that had been lyophilized, and 10 eyes received corneas kept in Optisol. Follow-up examinations included measurement of visual acuity (VA; Early Treatment Diabetic Retiropathy Study chart), topography, pachymetry, specular microscopy, constrast sensitivity, and confocal micorscopy.Results: All vairables improved similarly in both groups, without statistical differences between them, except for the uncorrected VA in the sixth postoperative month, which was better in the lyophilized group (0.46) compared with Optisol group (0.70). the best spectacle-corrected VA was 0.16 in the lyophilized group and 0.26 in the Optisol group. the mean endothelial cell count during the sixth postoperative month was 2778.5 in the lyophilized group and 2611.5 in the Optisol group. Optisol corneas had greater keratocyte density, and the keratocyte density improved in lyophilized corneas during follow-up.Conclusion: Lyophilized corneas can be used successfully for DALK to treat keratoconus with results similar to Optisol corneas.
Palavra-chave deep anterior lamellar keratoplasty
keratoconus
Optisol
lyophilization
Idioma Inglês
Data de publicação 2008-10-01
Publicado em Cornea. Philadelphia: Lippincott Williams & Wilkins, v. 27, n. 9, p. 1030-1036, 2008.
ISSN 0277-3740 (Sherpa/Romeo, fator de impacto)
Publicador Lippincott Williams & Wilkins
Extensão 1030-1036
Fonte http://dx.doi.org/10.1097/ICO.0b013e31817e903a
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000259662600011
Endereço permanente http://repositorio.unifesp.br/handle/11600/30958

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