Correlation Between Water-Drinking Test Outcomes and Body Mass Index in Primary Open-Angle Glaucoma Patients Under Clinical Treatment

Correlation Between Water-Drinking Test Outcomes and Body Mass Index in Primary Open-Angle Glaucoma Patients Under Clinical Treatment

Autor Lima, Veronica C. Autor UNIFESP Google Scholar
Prata, Tiago S. Autor UNIFESP Google Scholar
Lobo, Rodrigo A. B. Autor UNIFESP Google Scholar
Paranhos, Augusto Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Aims: the aim of this study was to evaluate the correlation between water-drinking test (WDT) outcomes and body mass index (BMI) in primary open-angle glaucoma (POAG) patients.Methods: This study enrolled 41 POAG patients (41 eyes) under glaucoma treatment. POAG was defined as any typical signs of glaucomatous optic neuropathy and/or visual-field finding, with open angle on gonioscopy. After inclusion, patients underwent weight and height measurements. the WDT was performed, consisting of a baseline intraocular pressure (IOP) measurement, followed by the ingestion of I L of tap water within 5 min. Then, IOP was measured four times, at 15-min intervals. IOP peak was considered the maximum value of the four measurements, and IOP fluctuation was defined as the difference between the peak and the baseline IOP.Results: the analysis of the IOP profile during the WDT revealed significant differences between groups with different BMIs. Patients with a higher BMI presented lower IOP peaks and fluctuation (P < 0.043; P < 0.001). There was also a significant correlation between the IOP fluctuation (both absolute [P < 0.024] and percentage [P < 0.021] values) and the following baseline parameters: BMI, weight, height, and cup-to-disc ratio.Conclusions: These data suggest that patients' individual characteristics, including BMI and weight, may influence the results of the WDT. in addition, patients with a higher BMI presented lower IOP fluctuation in the WDT.
Idioma Inglês
Data de publicação 2008-10-01
Publicado em Journal of Ocular Pharmacology and Therapeutics. New Rochelle: Mary Ann Liebert Inc, v. 24, n. 5, p. 513-516, 2008.
ISSN 1080-7683 (Sherpa/Romeo, fator de impacto)
Publicador Mary Ann Liebert Inc
Extensão 513-516
Fonte http://dx.doi.org/10.1089/jop.2007.0127
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000260068500011
Endereço permanente http://repositorio.unifesp.br/handle/11600/30957

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