Acute respiratory infection and influenza-like illness viral etiologies in Brazilian adults

Acute respiratory infection and influenza-like illness viral etiologies in Brazilian adults

Autor Bellei, Nancy Autor UNIFESP Google Scholar
Carraro, Emerson Autor UNIFESP Google Scholar
Perosa, Ana Autor UNIFESP Google Scholar
Watanabe, Aripuanã Sakurada Aranha Autor UNIFESP Google Scholar
Arruda, Eurico Google Scholar
Granato, Celso Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
São Paulo State Univ
Resumo Influenza-like illness (ILI) definitions have been used worldwide for influenza surveillance. These different case definitions can vary with regard to sensitivity and predictive values for laboratory confirmed influenza. the literature has indicated the inclusion of other viruses may be the cause of these variable results. the objective of the study was to evaluate ILI national sentinel criteria and viral etiologies in adults diagnosed with acute respiratory infection ARI) and/or ILI from 2001 to 2003 in São Paulo, Brazil. Clinical and laboratory evaluations were observed from 420 adults and collected on a daily basis from outpatient care units at University Hospital. the ILI definition included: fever plus at least one respiratory symptom (cough and/or sore throat) and one constitutional symptom (headache, malaise, myalgia, sweat or chills, or fatigue). DFA and RT-PCR for influenza, parainfluenza, respiratory syncytial virus, adenovirus, enterovirus, coronavirus, rhinovirus, and metapneumovirus were performed on nasal washes and 61.8% resulted positive. the respiratory viruses detected most often were influenza and rhinovirus. ILI was reported for 240/420 patients (57.1%), with influenza and rhinovirus etiologies accounting for 30.9% and 19.6%, respectively. Rhinovirus peak activity was concurrent with the influenza season. These findings highlight the implications of other viruses in ILI etiology and suggest that during the influenza season, this clinical overlap must be considered in the diagnosis and clinical management of patients.
Palavra-chave influenza
rhinovirus
influenza-like illness
Idioma Inglês
Financiador Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Número do financiamento FAPESP: 01/125796
Data de publicação 2008-10-01
Publicado em Journal of Medical Virology. Hoboken: Wiley-liss, v. 80, n. 10, p. 1824-1827, 2008.
ISSN 0146-6615 (Sherpa/Romeo, fator de impacto)
Publicador Wiley-Blackwell
Extensão 1824-1827
Fonte http://dx.doi.org/10.1002/jmv.21295
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000258734400021
Endereço permanente http://repositorio.unifesp.br/handle/11600/30930

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