Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

Cytogenetic biomonitoring in patients exposed to dental X-rays: comparison between adults and children

Autor Ribeiro, Daniel Araki Autor UNIFESP Google Scholar
Oliveira, G. de Google Scholar
Castro, Gláucia Monteiro de Autor UNIFESP Google Scholar
Angelieri, F. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Univ Metodista São Paulo
Resumo Objectives: the aim of the present study was to comparatively evaluate the DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) of exfoliated buccal mucosa cells from children and adults following dental X-ray exposure.Methods: A total of 17 adults and 17 children submitted to panoramic dental radiography were included in this study.Results: the results indicated no statistically significant differences (P > 0.05) in children's micronucleated oral mucosa cells before and after dental X-ray exposure. in the same way, no mutagenic effects were observed in adults following X-ray exposure. On the other hand, X-rays increased other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis and karyolysis in both groups. the comparative analysis between children and adults demonstrated no statistically significant differences in micronucleus frequency or (P > 0.05).Conclusions: in summary, these data indicate that dental paroramic radiography may not be a factor that includes chromosomal damage, but it is able to promote cytotoxicity. It seems that children are not more susceptible to the noxious activities induced by X-rays when compared with adults.
Palavra-chave buccal mucosa cells
X-ray
micronucleus test
Idioma Inglês
Financiador FAPESB
Número do financiamento FAPESB: 07/00345-7
Data de publicação 2008-10-01
Publicado em Dentomaxillofacial Radiology. London: British Inst Radiology, v. 37, n. 7, p. 404-407, 2008.
ISSN 0250-832X (Sherpa/Romeo, fator de impacto)
Publicador British Inst Radiology
Extensão 404-407
Fonte http://dx.doi.org/10.1259/dmfr/58548698
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000260169800007
Endereço permanente http://repositorio.unifesp.br/handle/11600/30924

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