Study on the prevalence of human papillomavirus in the anal canal of women with cervical intraepithelial neoplasia grade III

Study on the prevalence of human papillomavirus in the anal canal of women with cervical intraepithelial neoplasia grade III

Autor Veo, Carlos A. R. Autor UNIFESP Google Scholar
Saad, Sarhan S. Autor UNIFESP Google Scholar
Nicolau, Sergio M. Autor UNIFESP Google Scholar
Melani, Armando G. F. Autor UNIFESP Google Scholar
Denadai, Marcos Va. Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: the objective was to evaluate the prevalence of human papillomavirus (HPV) in the anal canal of women with cervical intraepithelial neoplasia (CIN) grade III.Study design: Two groups were compared. in group I (study group), 40 women who had undergone cervical biopsy with a histopathological result indicating CIN III were evaluated. Group II (control) consisted of 40 women with normal results from colposcopic examination and colpocytological tests. the women in group I who presented high-grade neoplasia in colpocytological tests underwent collection of material from the uterine cervix and anal canal for investigating HPV DNA using the Hybrid Capture II(R)) technique. Colposcopy and cervical biopsy were then performed. If CIN III was confirmed, HPV DNA was investigated in the material collected. in group II, colpocytological tests and colposcopy were performed and, if normal, the procedure was similar to that followed for group I, except that no biopsy was performed.Results: in group 1, 39 women (97.5%) were positive for HPV in the uterine cervix and 14 women (35%) in the anal canal. in group 11, only four women (10%) had a positive HPV test, for both the uterine cervix and the anal canal. Conclusions: the prevalence of HPV in the anal canal of the women with CIN III was greater than in the women without CIN III. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
Palavra-chave HPV
prevalence
anus
cervical cancer
Idioma Inglês
Data de publicação 2008-09-01
Publicado em European Journal of Obstetrics & Gynecology and Reproductive Biology. Amsterdam: Elsevier B.V., v. 140, n. 1, p. 103-107, 2008.
ISSN 0301-2115 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 103-107
Fonte http://dx.doi.org/10.1016/j.ejogrb.2008.02.024
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000259908100018
Endereço permanente http://repositorio.unifesp.br/handle/11600/30885

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