Severity scoring of atopic dermatitis: a comparison of two scoring systems

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dc.contributor.author Rullo, V. E. V. [UNIFESP]
dc.contributor.author Segato, A. [UNIFESP]
dc.contributor.author Kirsh, A. [UNIFESP]
dc.contributor.author Sole, D. [UNIFESP]
dc.date.accessioned 2016-01-24T13:51:32Z
dc.date.available 2016-01-24T13:51:32Z
dc.date.issued 2008-07-01
dc.identifier http://dx.doi.org/10.1016/S0301-0546(08)72551-5
dc.identifier.citation Allergologia Et Immunopathologia. Barcelona: Elsevier Doyma Sl, v. 36, n. 4, p. 205-211, 2008.
dc.identifier.issn 0301-0546
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/30782
dc.description.abstract Background: Atopic dermatitis (AD) is a chronic inflammatory pruritic skin heterogeneous disease, which does not have an objective tool able to permit comparison between patients and to monitor changes due to a specific treatment. Several assessment methods have been developed to evaluate the AD.Objectives: the aim of this study was to investigate the agreement between two observers in the assessment of the severity of AD applying SCORAD index and EASI in infants and young children with AD. the variations of parameters that compose each score, as well as the inter-observer variation for both scores, were also studied.Methods: We evaluated 42 infants and young children admitted and followed in a paediatric allergy centre (UNIFESP-EPM). All children met the diagnostic criteria for clinical AD established by Hanifin and Rajka. Two investigators graded the severity of AD, applying the SCORAD index and EASI. the two scoring systems assessed the variation between baseline evaluation and one month after treatment.Results: Significant correlations were observed comparing both scores for each physician and each evaluation. There were no differences between the mean SCORAD and EASI scores for each physician, in the two evaluations. There was a significant decrease in the mean total SCORAD and EASI score and its components, except for the item Upper Extremities EASIConclusion: Both scoring systems for AD are valid, reproducible and responsive in monitoring AD patients. Further studies will be necessary to investigate the development of AD and the best evaluation. SCORAD showed itself to be an excellent score to detect the development of AD, whereas the EASI are suitable to follow up in drug-effect studies of AD for research purposes. en
dc.format.extent 205-211
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Allergologia Et Immunopathologia
dc.rights Acesso restrito
dc.subject Atopic dermatitis en
dc.subject Score en
dc.subject Severity en
dc.subject Scoring system en
dc.title Severity scoring of atopic dermatitis: a comparison of two scoring systems en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, São Paulo, Brazil
dc.identifier.doi 10.1016/S0301-0546(08)72551-5
dc.description.source Web of Science
dc.identifier.wos WOS:000260621000006



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