Psychiatric comorbidity in epilepsy: A study comparing patients with mesial temporal sclerosis and juvenile myoclonic epilepsy

Psychiatric comorbidity in epilepsy: A study comparing patients with mesial temporal sclerosis and juvenile myoclonic epilepsy

Autor Araujo Filho, Gerardo Maria de Autor UNIFESP Google Scholar
Rosa, Vivianne Pellegrino Autor UNIFESP Google Scholar
Lin, Katia Autor UNIFESP Google Scholar
Sales Ferreira Caboclo, Luis Otavio Autor UNIFESP Google Scholar
Sakamoto, Americo Ceiki Autor UNIFESP Google Scholar
Targas Yacubian, Elza Marcia Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo We evaluated the frequency of psychiatric disorders (PDs) in a homogenous series of patients with temporal lobe epilepsy with mesial temporal sclerosis (TLE-MTS), as compared with patients with juvenile myoclonic epilepsy (JME), aiming to determine possible differences in psychiatric diagnoses between these two epileptic syndromes. Data from 170 patients with refractory TLE-MTS and from 100 patients with JME were reviewed and compared. the prevalence of PDs was high in both groups of patients with epilepsy: PDs were present in 85 patients with TLE-MTS (50%) and 49 patients with JME (49%). Among the TLE-MTS group, mood (25.8%), psychotic (15.8%), and anxiety (14.1%) disorders were the most frequent diagnoses, whereas anxiety and mood disorders (23 and 19%, respectively) were the most common among patients with JME. Psychoses were significantly associated with NITS (P < 0.01) and anxiety disorders with JME (P < 0.05). These findings suggest the existence of an anatomic correlation between PDs and brain structures involved in both epilepsy syndromes. (c) 2008 Elsevier Inc. All rights reserved.
Palavra-chave temporal lobe epilepsy
mesial temporal sclerosis
juvenile myoclonic epilepsy
psychiatric disorders
Idioma Inglês
Data de publicação 2008-07-01
Publicado em Epilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 13, n. 1, p. 196-201, 2008.
ISSN 1525-5050 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 196-201
Fonte http://dx.doi.org/10.1016/j.yebeh.2008.01.008
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000257009400034
Endereço permanente http://repositorio.unifesp.br/handle/11600/30779

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