Endometrial leukemia inhibitory factor as a predictor of pregnancy after in vitro fertilization

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dc.contributor.author Serafini, Paulo
dc.contributor.author Rocha, Andre M.
dc.contributor.author Osorio, Cyntia T.
dc.contributor.author Silva, Ismael da [UNIFESP]
dc.contributor.author Motta, Eduardo L. [UNIFESP]
dc.contributor.author Baracat, Edmund C.
dc.date.accessioned 2016-01-24T13:51:30Z
dc.date.available 2016-01-24T13:51:30Z
dc.date.issued 2008-07-01
dc.identifier http://dx.doi.org/10.1016/j.ijgo.2007.12.005
dc.identifier.citation International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 102, n. 1, p. 23-27, 2008.
dc.identifier.issn 0020-7292
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/30760
dc.description.abstract Objective: To determine whether there is an association between endometrial expression of leukemia inhibitory factor (LIF) in the luteal phase of the menstrual cycle preceding in vitro fertilization (IVF) and treatment outcome. Methods: Biopsy specimens from the endometria of 52 women in the luteal. phase were immunostained against LIF Embryo culture and transfer were done according to standard procedures. Results: Clinical pregnancy occurred in 39% of the women following IVF, and strong endometrial immunohistochemical staining for LIF was associated with pregnancy (P=0.01). the women with a strong LIF expression had a 6.4-fold higher chance of becoming pregnant than those with weaker intensities (P=0.005). Conclusion: Endometrial expression of LIF during the luteal phase can be used as a predictor of IVF success. (C) 2008 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. en
dc.format.extent 23-27
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof International Journal of Gynecology & Obstetrics
dc.rights Acesso restrito
dc.subject endometrial biopsy en
dc.subject endometrial receptivity en
dc.subject in vitro fertilization en
dc.subject leukemia inhibitory factor en
dc.subject luteal phase en
dc.subject tissue microarray en
dc.title Endometrial leukemia inhibitory factor as a predictor of pregnancy after in vitro fertilization en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Huntington Reproduct Ctr
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Hosp Canc AC Camargo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Huntington Reproduct Ctr, BR-04501000 São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Fac Med, Dept Gynecol, São Paulo, Brazil
dc.description.affiliation Hosp Canc AC Camargo, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Fac Med, Dept Gynecol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Fac Med, Dept Gynecol, São Paulo, Brazil
dc.identifier.doi 10.1016/j.ijgo.2007.12.005
dc.description.source Web of Science
dc.identifier.wos WOS:000257613500006



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