Idiopathic intracranial hypertension with and without papilloedema in a consecutive series of patients with chronic migraine

Idiopathic intracranial hypertension with and without papilloedema in a consecutive series of patients with chronic migraine

Author Vieira, D. S. S. Autor UNIFESP Google Scholar
Masruha, M. R. Autor UNIFESP Google Scholar
Goncalves, A. L. Autor UNIFESP Google Scholar
Zukerman, E. Google Scholar
Soares, C. A. Senne Google Scholar
Naffah-Mazzacoratti, M. Da Graca Autor UNIFESP Google Scholar
Peres, M. F. P. Autor UNIFESP Google Scholar
Institution Hosp Isralita Albert Einstein
Universidade Federal de São Paulo (UNIFESP)
Abstract Chronic migraine (CM) has been associated with idiopathic intracranial hypertension without papilloedema (IIHWOP), a significant percentage of these cases occurring in obese patients with intractable headache. A prospective study from February 2005 to June 2006 was made of 62 CM patients who fulfilled International Headache Society diagnostic criteria and had cerebral magnetic resonance venography (MRV) and lumbar puncture (LP) done. Two patients were excluded, six (10%) with elevated cerebrospinal fluid (CSF) open pressure (OP), five with body mass index (BMI) > 25. None of the patients had papilloedema or abnormal MRV. BMI and CSF OP were significantly correlated (r = 0.476, P < 0.001, Pearson's correlation test). Obesity (defined as BMI > 30) was a predictor of increase in intracranial pressure (defined as OP > 200 mmH(2)O) (f = 17.26, 95% confidence interval 6.0, 8.6; P < 0.001). From our study we strongly recommend that not only intractable CM patients with high BMI, but also first diagnosed patients with BMI > 30 should be systematically evaluated by a LP to rule out IIHWOP.
Keywords comorbidity
idiopathic intracranial hypertension
migraine
obesity
Language English
Date 2008-06-01
Published in Cephalalgia. London: Sage Publications Ltd, v. 28, n. 6, p. 609-613, 2008.
ISSN 0333-1024 (Sherpa/Romeo, impact factor)
Publisher Sage Publications Ltd
Extent 609-613
Origin http://dx.doi.org/10.1111/j.1468-2982.2008.01564.x
Access rights Closed access
Type Article
Web of Science ID WOS:000255479400005
URI http://repositorio.unifesp.br/handle/11600/30721

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