Update of the in vitro activity of daptomycin tested against 6710 Gram-positive cocci isolated in North America (2006)

Update of the in vitro activity of daptomycin tested against 6710 Gram-positive cocci isolated in North America (2006)

Author Castanheira, Mariana Google Scholar
Jones, Ronald N. Google Scholar
Sader, Helio S. Autor UNIFESP Google Scholar
Institution JMI Labs
Tufts Univ
Universidade Federal de São Paulo (UNIFESP)
Abstract Gram-positive bacterial strains (6710) consecutively collected during 2006 in hospitals located in the United States and Canada were tested by reference broth microdilution methods against daptomycin and comparison agents. Only 1 Staphylococcus aureus strain (0.01%) had nonsusceptible daptomycin MIC value as specified by published break points. S. aureus daptomycin MIC distributions from 2006 as compared with those of previous years did not show MIC creep. Resistance to other compounds, such as vancomycin, oxacillin and penicillin, did not adversely influence daptomycin activity. Daptomycin remains highly active against clinical Gram-positive isolates collected in North America. (C) 2008 Elsevier Inc. All rights reserved.
Keywords daptomycin
MRSA
vancomycin resistance
Language English
Date 2008-06-01
Published in Diagnostic Microbiology and Infectious Disease. New York: Elsevier B.V., v. 61, n. 2, p. 235-239, 2008.
ISSN 0732-8893 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 235-239
Origin http://dx.doi.org/10.1016/j.diagmicrobio.2008.01.016
Access rights Closed access
Type Article
Web of Science ID WOS:000256489400019
URI http://repositorio.unifesp.br/handle/11600/30700

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