Outbreak of OXY-2-producing Klebsiella oxytoca in a renal transplant unit

Outbreak of OXY-2-producing Klebsiella oxytoca in a renal transplant unit

Author Zarate, Mariela Soledad Google Scholar
Gales, Ana C. Autor UNIFESP Google Scholar
Picao, Renata C. Autor UNIFESP Google Scholar
Pujol, Gervasio Soler Google Scholar
Lanza, Alejandra Google Scholar
Smayevsky, Jorgelina Google Scholar
Institution CEMIC
Universidade Federal de São Paulo (UNIFESP)
Abstract We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Grant number CNPq: 307714/2006-3
Date 2008-06-01
Published in Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 46, n. 6, p. 2099-2101, 2008.
ISSN 0095-1137 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Microbiology
Extent 2099-2101
Origin http://dx.doi.org/10.1128/JCM.00194-08
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000258695500038
URI http://repositorio.unifesp.br/handle/11600/30676

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