Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns

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dc.contributor.author Mathis, Maria Alice de
dc.contributor.author Rosario, Maria Conceicao do [UNIFESP]
dc.contributor.author Diniz, Juliana Belo
dc.contributor.author Torres, Albina Rodrigues
dc.contributor.author Shavitt, Roseli Gedanki
dc.contributor.author Ferrao, Ygor Arzeno
dc.contributor.author Fossaluza, Victor
dc.contributor.author Braganca Pereira, Carlos Alberto de
dc.contributor.author Miguel, Euripedes Constantino
dc.date.accessioned 2016-01-24T13:49:43Z
dc.date.available 2016-01-24T13:49:43Z
dc.date.issued 2008-04-01
dc.identifier http://dx.doi.org/10.1016/j.eurpsy.2008.01.002
dc.identifier.citation European Psychiatry. Paris: Elsevier France-editions Scientifiques Medicales Elsevier, v. 23, n. 3, p. 187-194, 2008.
dc.identifier.issn 0924-9338
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/30564
dc.description.abstract Purpose. - This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset.Methods. - Three hundred and thirty OCD patients were consecutively recruited and interviewed using the following structured interviews: Yale-Brown Obsessive Compulsive Scale; Yale Global Tic Severity Scale and the Structured Clinical Interview for DSM-IV. Data were analyzed with regression and cluster analysis.Results. - Lower age at onset was associated with a higher probability of having comorbidity with tic, anxiety, somatoform, eating and impulse-control disorders. Longer illness duration was associated with lower chance of having tics. Female gender was associated with anxiety, eating and impulse-control disorders. Tic disorders were associated with anxiety disorders and attention-deficit/hyperactivity disorder. No cutoff age at onset was found to clearly divide the sample in homogeneous subgroups. However, cluster analyses revealed that differences started to emerge at the age of 10 and were more pronounced at the age of 17, suggesting that these were the best cut-off points on this sample.Conclusions. - Age at onset is associated with specific comorbidity patterns in OCD patients. More prominent differences are obtained when analyzing age at onset as an absolute value. (C) 2008 Elsevier Masson SAS. All rights reserved. en
dc.format.extent 187-194
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof European Psychiatry
dc.rights Acesso restrito
dc.subject obsessive-compulsive disorder en
dc.subject age at onset en
dc.subject comorbidity en
dc.subject early onset en
dc.subject late onset en
dc.title Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Porto Alegre Inst Univ Ctr
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ São Paulo, Sch Med, Dept Psychiat, BR-05403010 São Paulo, Brazil
dc.description.affiliation Botucatu Med Sch, Dept Neurol & Psychiat, Botucatu, SP, Brazil
dc.description.affiliation Porto Alegre Inst Univ Ctr, Porto Alegre, RS, Brazil
dc.description.affiliation Univ São Paulo, Math & Stat Inst, BR-05508 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Psychiat, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Psychiat, São Paulo, Brazil
dc.identifier.doi 10.1016/j.eurpsy.2008.01.002
dc.description.source Web of Science
dc.identifier.wos WOS:000254884100004

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