Brazilian normal static bone histomorphometry: effects of age, sex, and race

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dc.contributor.author Dos Reis, Luciene M.
dc.contributor.author Batalha, Joao R.
dc.contributor.author Munoz, Daniel R.
dc.contributor.author Borelli, Aurelio
dc.contributor.author Correa, Pedro H. S.
dc.contributor.author Carvalho, Aluizio B.
dc.contributor.author Jorgetti, Vanda
dc.date.accessioned 2016-01-24T13:49:10Z
dc.date.available 2016-01-24T13:49:10Z
dc.date.issued 2007-11-01
dc.identifier http://dx.doi.org/10.1007/s00774-007-0778-4
dc.identifier.citation Journal of Bone and Mineral Metabolism. Tokyo: Springer Tokyo, v. 25, n. 6, p. 400-406, 2007.
dc.identifier.issn 0914-8779
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/30118
dc.description.abstract Bone histomorphometry values for normal individuals within different populations have been well established. We studied iliac crest bone samples from 125 healthy Brazilian subjects. the effect of sex, race, and age variables on histomorphometric parameters was evaluated. Bone volume showed a trend to decrease with age in both sexes, being significantly higher in black females and Caucasian males. Interactions among sex, race, and age had no effect on trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp). However, age had a significant effect on Tb.Th and Tb.Sp, and sex had an impact on Tb.Sp. Trabecular number (Tb.N) was higher in black females than in males and was higher in Asian males than in females. Among females, Tb.N was lower in Asians than in other races and was higher in blacks than in Caucasians and or in those of mulattos. in addition, Tb.N was higher in males under 10 than in males over 50 years old, was higher in females under 10 than in females in any other age bracket, and was lower in females in the 41-50 age bracket than in younger females. Osteoid volume and osteoid surface were significantly higher in males than in females, and a significant age-related difference in osteoid thickness was observed. No significant sex-related or race-related differences were found in terms of resorption, although eroded surface decreased with age. in conclusion, sex, race, and age, as well as interactions among these three variables, were found to affect some static histomorphometric indexes in healthy Brazilian subjects. en
dc.format.extent 400-406
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Journal of Bone and Mineral Metabolism
dc.rights Acesso restrito
dc.subject bone histomorphometry en
dc.subject age-related bone loss en
dc.subject race and sex differences en
dc.subject normal iliac bone en
dc.title Brazilian normal static bone histomorphometry: effects of age, sex, and race en
dc.type Artigo
dc.rights.license http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ São Paulo, Sch Med, Dept Nephrol, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Sch Med, Dept Endocrinol, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Sch Med, Dept Legal Med, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Sch Med, Dept Radiol, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Inst Biomed Sci, Dept Physiol & Biophys, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Med, Div Nephrol, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Med, Discipline Clin Med, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Med, Div Nephrol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Med, Discipline Clin Med, São Paulo, Brazil
dc.identifier.doi 10.1007/s00774-007-0778-4
dc.description.source Web of Science
dc.identifier.wos WOS:000250538500008



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