Effects of 2 or 5 consecutive exercise days on adipocyte area and lipid parameters in Wistar rats

Effects of 2 or 5 consecutive exercise days on adipocyte area and lipid parameters in Wistar rats

Author Guerra, Ricardo Luís Fernandes Autor UNIFESP Google Scholar
Prado, Wagner Luiz do Autor UNIFESP Google Scholar
Cheik, Nadia Carla Google Scholar
Viana, Fabiana Pavan Google Scholar
Botero, João Paulo Google Scholar
Vendramini, Regina Celia Google Scholar
Carlos, Iracilda Zeppone Google Scholar
Rossi, Elizeu Antonio Google Scholar
Dâmaso, Ana Raimunda Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Paulista State Univ Araraquara
Abstract Background: Exercise has been prescribed in the treatment and control of dyslipidemias and cholesterolemia, however, lipid responses to different training frequencies in hypercholesterolemic men have been inconsistent. We sought to verify if different frequencies of continuous moderate exercise (2 or 5 days/week, swimming) can, after 8 weeks, promote adaptations in adipocyte area and lipid parameters, as well as body weight and relative weight of tissues in normo and hypercholesterolemic adult male rats.Methods: Normal cholesterol chow diet or cholesterol-rich diet (1% cholesterol plus 0.25% cholic acid) were freely given during 8 weeks to the rats divided in 6 experimentals groups: sedentary normal cholesterol chow diet (C); sedentary cholesterol-rich diet (H); 5x per week continuous training normal cholesterol chow diet (TC5) and cholesterol-rich diet (TH5); 2x per week continuos traning normal cholesterol chow diet (TC2) and cholesterol-rich diet (TH2).Results: No changes were observed in lipid profile in normal cholesterol chow diet, but both 2 a 5 days/week exercise improved this profile in cholesterol-rich diet. Body weight gain was lower in exercised rats. Decrease in retroperitoneal and epididymal relative weights as well as reductions in adipocyte areas under all diets types were observed only in 5 days/week, while 2 days/week showed improvements mainly in cholesterol-rich diet rats.Conclusion: Our results confirm the importance of exercise protocols to control dyslipidemias and obesity in rats. the effects of 5 days/week exercise were more pronounced compared with those of 2 consecutive days/week training.
Language English
Date 2007-07-02
Published in Lipids in Health and Disease. London: Biomed Central Ltd, v. 6, 8 p., 2007.
ISSN 1476-511X (Sherpa/Romeo, impact factor)
Publisher Biomed Central Ltd
Extent 8
Origin https://dx.doi.org/10.1186/1476-511X-6-16
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000251131400001
URI https://repositorio.unifesp.br/handle/11600/29871

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