Allogenous bone grafts improved by bone marrow stem cells and platelet growth factors: Clinical case reports

Allogenous bone grafts improved by bone marrow stem cells and platelet growth factors: Clinical case reports

Autor Cerruti, Humberto Filho Google Scholar
Kerkis, Irina Google Scholar
Kerkis, Alexandre Google Scholar
Tatsui, Nelson Hidekazu Google Scholar
Neves, Adriana da Costa Google Scholar
Bueno, Daniela Franco Google Scholar
Pereira da Silva, Marcelo Cavenaghi Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Clin CERA LTDA
Universidade de São Paulo (USP)
Resumo In order to increase the amount of available bone where dental implants must be placed, the present study has associated platelet-rich plasma (PRP) and mononuclear cells (MNCs) from bone marrow aspirate and bone scaffold (BS) in 32 patients aged between 45 and 75 years old. the MNC attainment and the adherence to the BS were confirmed through histology, cell culture, and scanning electron microscopy. the clinical results, analyzed by computed tomography, have showed that the scaffolds were well integrated and adapted to the cortical bone. We can conclude that the process of healing observed in the patients was due to the presence of mesenchymal stem cell in MNC fraction in the bone grafts.
Assunto alveolar ridge augmentation
blood platelets
bone marrow cells
dental implantation
stem cell
Idioma Inglês
Data 2007-04-01
Publicado em Artificial Organs. Hoboken: Wiley-Blackwell, v. 31, n. 4, p. 268-273, 2007.
ISSN 0160-564X (Sherpa/Romeo, fator de impacto)
Editor Wiley-Blackwell
Extensão 268-273
Fonte http://dx.doi.org/10.1111/j.1525-1594.2007.00374.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000245602000005
URI http://repositorio.unifesp.br/handle/11600/29651

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