Treatment of moderate obstructive sleep apnea syndrome with acupuncture: A randomised, placebo-controlled pilot trial

Treatment of moderate obstructive sleep apnea syndrome with acupuncture: A randomised, placebo-controlled pilot trial

Author Freire, Anaflavia de Oliveira Autor UNIFESP Google Scholar
Sugai, Gisele C. M. Google Scholar
Chrispin, Fernanda Silveira Google Scholar
Togeiro, Sonia Maria Google Scholar
Yamamura, Ysao Google Scholar
Mello, Luiz Eugenio Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Background and purpose: To investigate the efficacy of acupuncture in the treatment of moderate obstructive sleep apnea syndrome (OSAS), assessed by polysomnography (PSG) and questionnaires of functional quality of life (SF-36) and excessive daytime sleepiness (Epworth).Patients and methods: We performed a randomised, placebo-controlled, single-blinded study, with blinded evaluation on 36 patients presenting an apnea/hypopnea index (AHI) of 15-30/h, assessed by PSG. the study took place at the Public Hospital of the Universidade Federal de S (a) over tildeo Paulo, Brazil, in the Division of Sleep Disorders of the Department of Psychobiology, between January, 2002 and August, 2004. Patients were randomly assigned to three groups: the acupuncture group (n = 12); the sham group, submitted to needle insertion in non-acupoints (n = 12); and the control group, receiving no treatment (n = 12). Patients received acupuncture or sham acupuncture once a week for 10 weeks.Results: Twenty-six patients completed the study. the AHI (P = 0.005), the apnea index (AI) (P = 0.008) and the number of respiratory events (P = 0.005) decreased significantly in the acupuncture group but not in the sham group. On the other hand, the control group displayed significant deterioration in some of the polysomnographic parameters, with a significant increase in the n umber of respiratory events (P = 0.025). Acupuncture treatment significantly improved (before vs. after treatment) several dimensions of the SF-36 and Epworth questionnaires. There was no significant association between changes in the body mass index (BMI) and AHI.Conclusions: Acupuncture is more effective than sharn acupuncture in ameliorating the respiratory events of patients presenting with moderate OSAS. (c) 2006 Elsevier B.V. All rights reserved.
Keywords acupuncture
obstructive sleep apnea syndrome
quality of life
excessive daytime sleepiness
Language English
Date 2007-01-01
Published in Sleep Medicine. Amsterdam: Elsevier B.V., v. 8, n. 1, p. 43-50, 2007.
ISSN 1389-9457 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 43-50
Access rights Closed access
Type Article
Web of Science ID WOS:000244399100008

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