Chromosomal and cardiac anomalies in fetuses with intracardiac echogenic foci

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dc.contributor.author Goncalves, T. R. M.
dc.contributor.author Zamith, M. M.
dc.contributor.author Murta, C. G. V.
dc.contributor.author Bussamra, L. C.
dc.contributor.author Torloni, M. R.
dc.contributor.author Moron, A. F.
dc.date.accessioned 2016-01-24T12:41:34Z
dc.date.available 2016-01-24T12:41:34Z
dc.date.issued 2006-11-01
dc.identifier http://dx.doi.org/10.1016/j.ijgo.2006.06.020
dc.identifier.citation International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 95, n. 2, p. 132-137, 2006.
dc.identifier.issn 0020-7292
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/29233
dc.description.abstract Objective: To evaluate the prevalence of intracardiac echogenic foci (ICEF) and the association between ICEF and chromosomal and cardiac anomalies in Brazilian women. Methods: in a cross-sectional observational study, 373 of the 23,360 genetic sonograms performed at a private maternal-fetal medicine clinic over 5 years showed intracardiac echogenic foci (ICEF). These 373 sonograms were reviewed for chromosomal and cardiac anomalies and associations were analyzed using the chi(2) test or the Fisher exact test. P < 0.05 was considered significant. Results: the prevalence of ICEF was 1.7%. Cardiac anomalies were detected in 10 sonograms (2.7%) and chromosomal anomalies in 14 (3.7%). There were cardiac defects in 6 (1.7%) of the 359 euploid fetuses with isolated ICEF of the 373 women who had fetuses with ICEF, 295 were younger than 35 years and 78 were 35 years or older. There were 6 fetuses (2.1%) with aneuploidy in the younger group and 8 (10.3%) in the older group. Conclusion: the prevalence of ICEF was 1.7%, and there was an association between cardiac and chromosomal anomalies. Women carrying fetuses with ICEF should be offered fetal echocardiography and karyotyping. (c) 2006 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. en
dc.format.extent 132-137
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof International Journal of Gynecology & Obstetrics
dc.rights Acesso restrito
dc.subject intracardiac echogenic focus en
dc.subject fetal heart en
dc.subject Down syndrome en
dc.subject karyotypic abnormality en
dc.subject fetal aneuploidy en
dc.subject ultrasound en
dc.title Chromosomal and cardiac anomalies in fetuses with intracardiac echogenic foci en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Hosp & Maternidade Santa Joana
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Hosp & Maternidade Santa Joana, Fetal Med Unit, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Fetal Med Unit, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Fetal Med Unit, São Paulo, Brazil
dc.identifier.doi 10.1016/j.ijgo.2006.06.020
dc.description.source Web of Science
dc.identifier.wos WOS:000242449700006



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