Pre-surgical evaluation and surgical treatment in children with extratemporal epilepsy

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dc.contributor.author Centeno, Ricardo Silva
dc.contributor.author Yacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.author Sakamoto, Americo Ceiki
dc.contributor.author Ferraz, Antonio Fernando Patriani
dc.contributor.author Carrete Junior, Henrique
dc.contributor.author Cavalheiro, Sergio
dc.date.accessioned 2016-01-24T12:41:21Z
dc.date.available 2016-01-24T12:41:21Z
dc.date.issued 2006-08-01
dc.identifier http://dx.doi.org/10.1007/s00381-006-0145-0
dc.identifier.citation Childs Nervous System. New York: Springer, v. 22, n. 8, p. 945-959, 2006.
dc.identifier.issn 0256-7040
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/29061
dc.description.abstract Introduction This review summarizes some patterns of pre-surgical evaluation and surgical treatment of extratemporal epilepsy in pediatric patients with medically refractory seizures, whose ictal behavior is variable. the most effective treatment for intractable partial epilepsy is a focal cortical resection with excision of the epileptogenic zone (the area of ictal onset and initial seizure propagation). This might be risky, though, in the case of a widespread lesion, sometimes encroaching one or more lobes, given the risk to the functional cerebral cortex. An anterior temporal lobectomy might prove more effective then in preventing seizures with fewer potential complications. If partial extratemporal epilepsy is associated with pharmaco-resistant seizures, the preoperative evaluation and operative strategy are determined according to the epileptogenic zone and to the relationship between a substrate-directed disorder and eloquent areas. the pediatric treatment of extratemporal epilepsy is aimed at controlling the seizures, avoiding morbidity, and improving the patient's quality of life through psychosocial integration. Since the immature brain is more plastic than when mature, the recovery of functions after surgery is greater in children than in adults.Recommendation Early surgery is recommended for children with intractable epilepsy, and is now accepted as an important therapeutic modality also for children with chronic epilepsy.Conclusion Technological advances in the last two decades, mainly in neuroimaging, have led many medical centers to consider surgical treatment of epilepsy, accuracy being granted by MRI-based neuronavigation systems-an interface between the lesion seen in the preoperative magnetic resonance imaging (MRI) and the operative field, often invisible to the surgeon. en
dc.format.extent 945-959
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartof Childs Nervous System
dc.rights Acesso restrito
dc.subject extratemporal pediatric epilepsy en
dc.subject pre-surgical evaluation en
dc.subject neuronavigation en
dc.subject pediatric epilepsy surgery en
dc.title Pre-surgical evaluation and surgical treatment in children with extratemporal epilepsy en
dc.type Resenha
dc.rights.license http://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Dept Neurol Neurocirurgia, Disciplina Neurocirurgia, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Neurol Neurocirurgia, Disciplina Neurocirurgia, BR-04024002 São Paulo, Brazil
dc.identifier.doi 10.1007/s00381-006-0145-0
dc.description.source Web of Science
dc.identifier.wos WOS:000239170500021



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