Clinical co-morbidities in obstructive sleep apnea syndrome treated with mandibular repositioning appliance

Clinical co-morbidities in obstructive sleep apnea syndrome treated with mandibular repositioning appliance

Autor Machado, Marco Antonio Cardoso Autor UNIFESP Google Scholar
Carvalho, Luciane Bizari Coin de Autor UNIFESP Google Scholar
Juliano, Maria Ligia Autor UNIFESP Google Scholar
Taga, Marcel Frederico de Lima Autor UNIFESP Google Scholar
Prado, Lucila Bizari Fernandes do Autor UNIFESP Google Scholar
Prado, Gilmar Fernandes do Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Introduction: Intraoral mandibular repositioner appliances (IOMRAs) are designed to enlarge pharyngeal airway space advancing the mandible and increasing genioglossus tone during sleep. Obstructive sleep apnea syndrome (OSAS) treatment with IOMRAs is beneficial, but there is a lack of studies in the literature defining the target population more inclined to respond to this treatment.Methods: We contacted by telephone 188 previously treated patients with IOMRA, detecting 20 not improved patients (Study Group). Twenty improved patients of the remaining 168 were randomly paired according to gender, age, apnea, and hypopnea index as Control Group. Both groups answered questionnaires for diagnosis of sleep disorders, depression, anxiety, and the Epworth sleepiness scale. We did a descriptive and inferential statistical analysis. the inferential analysis was divided into two steps: univariate analysis using Fischer exact test and a multiple inferential analysis using a stepwise regression model.Results: Although the final model included only insomnia, we concluded that the presence of gastric, neurological and rheumatic diseases also tended to be associated with the self-perception of non-improvement. the association between the accumulation of gastric, neurological, and rheumatic diseases and insomnia and improvement demonstrated that an increase in one of these diseases correspond to a two-fold increase in the chance of non-improvement.Conclusions: Insomnia was the most important factor compromising the, success of OSAS treatment with IOMRAs, and the isolated presence of gastric, neurological and rheumatic diseases, but especially their combination, reduces the perception rate of welt-succeeded treatment with IOMRAs. (c) 2005 Elsevier B.V. All rights reserved.
Palavra-chave insomnia
sleep apnea
intraoral appliances
adult
Idioma Inglês
Data de publicação 2006-06-01
Publicado em Respiratory Medicine. London: W B Saunders Co Ltd, v. 100, n. 6, p. 988-995, 2006.
ISSN 0954-6111 (Sherpa/Romeo, fator de impacto)
Publicador W B Saunders Co Ltd
Extensão 988-995
Fonte http://dx.doi.org/10.1016/j.rmed.2005.10.002
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000238016500005
Endereço permanente http://repositorio.unifesp.br/handle/11600/28915

Exibir registro completo




Arquivo

Nome: WOS000238016500005.pdf
Tamanho: 151.7KB
Formato: PDF
Descrição:
Abrir arquivo

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta