Coronary stenting and inflammation: Implications for further surgical and medical treatment

Coronary stenting and inflammation: Implications for further surgical and medical treatment

Autor Gomes, Walter José Autor UNIFESP Google Scholar
Buffolo, E. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo The introduction of percutaneous coronary interventions (PCI) with stent implant has substantially shifted the treatment of coronary artery disease. the current approach to coronary artery disease treatment includes first-choice PCI in selected subgroups; and once this therapy fails, frequently the patient is referred for coronary artery bypass graft surgery. However, evidence of chronic inflammatory reaction and endothelial dysfunction after PCI has been emerging and that might be interfering with patient outcome when surgical or medical treatments are subsequently required. the clinical significance of these complications after PCI, herein examined, has been less studied and needs better assessment. Also, the premise that coronary artery bypass graft surgery can safely be performed in patients with coronary stenting failure may not hold true, as graft patency might be adversely affected. Furthermore, the superimposed inflammatory reaction may blunt the efficacy of medical treatment.
Idioma Inglês
Data de publicação 2006-05-01
Publicado em Annals of Thoracic Surgery. New York: Elsevier B.V., v. 81, n. 5, p. 1918-1925, 2006.
ISSN 0003-4975 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 1918-1925
Fonte http://dx.doi.org/10.1016/j.athoracsur.2005.10.014
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:000237001700076
Endereço permanente http://repositorio.unifesp.br/handle/11600/28881

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