Cutaneous T-cell lymphoma with HTLV-I infection: clinical overlap with adult T-cell leukemia/lymphoma

Cutaneous T-cell lymphoma with HTLV-I infection: clinical overlap with adult T-cell leukemia/lymphoma

Autor Sakamoto, F. H. Google Scholar
Colleoni, GWB Google Scholar
Teixeira, S. P. Google Scholar
Yamamoto, M. Google Scholar
Michalany, N. S. Google Scholar
Almeida, F. A. Google Scholar
Chiba, A. K. Google Scholar
Petri, V Google Scholar
Fernandes, M. A. Google Scholar
Pombo-de-Oliveira, M. S. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Ctr Pesquisas
Resumo Adult T-cell leukemia/lymphoma (ATLL) is a malignant proliferation of mature helper T lymphocytes, 1 and is caused by human T-lymphotropic virus type I (HTLV-I);(2) an HTLV-I infection endemic in the Caribbean, south-western Japan, South America and Africa.(3,4) Seroepidemiological studies suggest that it is also endemic in Brazil.(5) Although carriers of HTLV-I show polyclonal integration of virus in T lymphocytes, only patients with ATLL of various subtypes show monoclonal integration of HTLV-I in tumor cells.(6,7) Cutaneous T-cell lymphomas ( CTCL) are a group of primary cutaneous lymphoproliferative diseases(8) with unknown etiology.(9) the two most common presentations of CTCL are mycosis fungoides (MF) and Sezary syndrome (SS).(10-13) However, both CTCL categories can easily resemble ATLL. Therefore, in HTLV-I endemic areas, differentiation between ATLL and CTCL must be performed, as they have different prognoses and treatment approaches.(14).
Idioma Inglês
Data de publicação 2006-04-01
Publicado em International Journal of Dermatology. Oxford: Blackwell Publishing, v. 45, n. 4, p. 447-449, 2006.
ISSN 0011-9059 (Sherpa/Romeo, fator de impacto)
Publicador Blackwell Publishing
Extensão 447-449
Fonte http://dx.doi.org/10.1111/j.1365-4632.2006.02687.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000236585200022
Endereço permanente http://repositorio.unifesp.br/handle/11600/28836

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