Can childhood trauma predict response to topiramate in borderline personality disorder?

Can childhood trauma predict response to topiramate in borderline personality disorder?

Autor Prado-Lima, PAS do Google Scholar
Kristensen, C. H. Google Scholar
Bacaltchuck, J. Google Scholar
Instituição Pontificia Univ Catolica Rio Grande Sul
Univ Vale Rio Sinos
Universidade Federal de São Paulo (UNIFESP)
Janssen Cilag Farmaceut
Resumo We report on a woman with borderline personality disorder and a history of childhood trauma that showed significant clinical response with low dosage of topiramate. We propose that topiramate changed some of the main features of this disorder, such as catastrophic reaction to real or imaginary abandonment or rejection, improving adaptive functioning. We hypothesize that topiramate might facilitate memory extinction, therefore decreasing emotional and behavioural reactivity.
Assunto borderline personality disorder
child abuse
post-traumatic stress disorder
topiramate
Idioma Inglês
Data 2006-04-01
Publicado em Journal of Clinical Pharmacy and Therapeutics. Oxford: Blackwell Publishing, v. 31, n. 2, p. 193-196, 2006.
ISSN 0269-4727 (Sherpa/Romeo, fator de impacto)
Editor Blackwell Publishing
Extensão 193-196
Fonte http://dx.doi.org/10.1111/j.1365-2710.2006.00716.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000237472300012
URI http://repositorio.unifesp.br/handle/11600/28833

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