Urticaria as a cutaneous sign of adult-onset Still's disease

Urticaria as a cutaneous sign of adult-onset Still's disease

Autor Criado, Roberta F. J. Google Scholar
Criado, Paulo Ricardo Google Scholar
Vasconcellos, Cidia Google Scholar
Szajubok, Jose Carlos M. Google Scholar
Michalany, Nilceo S. Google Scholar
Kadunc, Bogdana Victoria Google Scholar
Costa Martins, Jose Eduardo Google Scholar
Instituição Fac Med ABC
Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Hosp Servidor Publ Municipal
Resumo Background. the cardinal signs and symptoms of adult-onset Still's disease (AOSD) include periodic fever, arthralgia and arthritis, lymphadenopathy, hepatosplenomegaly, an evanescent rash accompanied by neutrophilic granulocytosis, and a negative rheumatoid factor and antinuclear antibody test.Objective To alert clinicians and dermatologists to internal diseases such as AOSD when assisting patients with urticarial eruptions and systemic symptoms.Methods: A case report of a 52-year-old white woman who received conventional therapy for urticaria for 3 years, with no improvement. Following this period, a diagnosis of AOSD was performed based on the presence of systemic symptoms.Results: the inflammatory activity markers decreased by the second month of methotrexate therapy; however, the cutaneous lesions failed to disappear. Thalidomide was initiated, and total improvement of the cutaneous lesions was observed after 2 weeks.Conclusion: Urticarial rash is an uncommon presentation of AOSD, and clinicians must be alert to the possibility of a mis-diagnosis in these cases.
Idioma Inglês
Data 2006-03-01
Publicado em Journal of Cutaneous Medicine and Surgery. Hamilton: B C Decker Inc, v. 10, n. 2, p. 99-103, 2006.
ISSN 1203-4754 (Sherpa/Romeo, fator de impacto)
Editor B C Decker Inc
Extensão 99-103
Fonte http://dx.doi.org/10.2310/7750.2006.00017
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000248049800008
URI http://repositorio.unifesp.br/handle/11600/28789

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