Effects of progesterone on sleep: A possible pharmacological treatment for sleep-breathing disorders?

Effects of progesterone on sleep: A possible pharmacological treatment for sleep-breathing disorders?

Autor Andersen, Monica Levy Autor UNIFESP Google Scholar
Bittencourt, Lia Rita Azeredo Autor UNIFESP Google Scholar
Antunes, I. B. Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Progesterone is present in a wide spectrum of biological activity within a variety of tissues. This hormone is also known to affect reproduction, sleep quality, respiration, mood, appetite, learning, memory and sexual activity. Progesterone exerts a sleep induction or hypnotic effect and is a potent respiratory stimulant that has been associated to a decrease in the number of central and obstructive sleep apnea episodes in men. the literature also contains a substantial amount of data on the effect of apnea in women with obesity-hypoventilation during menopause. This review attempts to outline the specific role of progesterone in normal sleep and breathing as well as its possible therapeutic effects in the treatment of sleep-disordered breathing.
Assunto progesterone
sleep
sleep apnea
breathing
hormonal control
Idioma Inglês
Data 2006-01-01
Publicado em Current Medicinal Chemistry. Sharjah: Bentham Science Publ Ltd, v. 13, n. 29, p. 3575-3582, 2006.
ISSN 0929-8673 (Sherpa/Romeo, fator de impacto)
Editor Bentham Science Publ Ltd
Extensão 3575-3582
Fonte http://dx.doi.org/10.2174/092986706779026200
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:000242002600007
URI http://repositorio.unifesp.br/handle/11600/28686

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