Venous-arterial Doppler ratios in the prediction of acidemia at birth in pregnancies with placental insufficiency

Venous-arterial Doppler ratios in the prediction of acidemia at birth in pregnancies with placental insufficiency

Author Carvalho, F. H. C. Google Scholar
Moron, A. F. Google Scholar
Mattar, Rosiane Autor UNIFESP Google Scholar
Murta, C. G. V. Google Scholar
Santana, R. M. Google Scholar
Barbosa, M. M. Google Scholar
Torloni, M. R. Google Scholar
Vasques, F. A. P. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Ceara Fed Univ
Abstract Objectives: Investigate the prediction of birth acidemia in pregnancies with placental insufficiency using two newly created venous-arterial Doppler ratios: pulsatility index (PI) of the cluctus venosus (DV) over PI of the middle cerebral artery (MCA) and PI of the DV over PI of the umbilical artery and establish cut-off values for this prediction. Methods:This was a prospective cross-sectional study involving 47 patients with placental insufficiency managed in two Brazilian hospitals. All pregnancies were singleton, over 26 weeks of age and without structural or chromosome anomalies. A ROC curve was calculated for the venous-arterial ratios (independent variable) and acidernia (dependent variable). Results: the DV/AU PI ratio was not a good predictor of acidemia at birth. the DV/MCA PI ratio was related to fetal acidernia (area under the ROC curve 0.785, p = 0.004). the cut-off value was 0.582, sensibility 66.7%, specificity 77.1% and accuracy 74.5%. Conclusions: the DV/MCA PI ratio is adequate for the diagnosis of acidemia at birth in pregnancies with placental insufficiency. the cut-off value was 0.582. Copyright (c) 2006 S. Karger AG, Basel.
Keywords Doppler velocimetry
ductus venosus
venous-arterial ratio
fetal acidemia
Language English
Date 2006-01-01
Published in Fetal Diagnosis and Therapy. Basel: Karger, v. 21, n. 5, p. 418-423, 2006.
ISSN 1015-3837 (Sherpa/Romeo, impact factor)
Publisher Karger
Extent 418-423
Origin http://dx.doi.org/10.1159/000093883
Access rights Closed access
Type Article
Web of Science ID WOS:000239896300005
URI http://repositorio.unifesp.br/handle/11600/28676

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