Transcranial Doppler in adult patients with sickle cell disease

Transcranial Doppler in adult patients with sickle cell disease

Autor Silva, G. S. Google Scholar
Vicari, P. Google Scholar
Figueiredo, M. S. Google Scholar
Castelo, A. Google Scholar
Valadi, N. Google Scholar
Massaro, A. R. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Med Coll Georgia
Resumo Background: Transcranial Doppler (TCD) is the key test in determining the need for prophylactic blood transfusion to prevent stroke in children with sickle cell disease (SCD). the role of TCD in assessing stroke risk in adults with SCD as well as the pattern of TCD velocities in these patients are still undetermined. Methods: the authors compared TCD velocities in SCD adults (n = 56) with those of healthy controls (n = 56). Results: Velocities in SCD adults were lower than those found in children and higher than in controls and negatively correlated to hematocrit in both groups. Conclusion: the pattern of TCD velocities in adults with SCD is different from that described in children. Age-specific TCD criteria may assist the detection of stroke risk in these patients. Copyright (c) 2006 S. Karger AG, Basel.
Palavra-chave Transcranial Doppler
sickle cell disease
stroke
Idioma Inglês
Data de publicação 2006-01-01
Publicado em Cerebrovascular Diseases. Basel: Karger, v. 21, n. 1-2, p. 38-41, 2006.
ISSN 1015-9770 (Sherpa/Romeo, fator de impacto)
Publicador Karger
Extensão 38-41
Fonte http://dx.doi.org/10.1159/000089592
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000234169600006
Endereço permanente http://repositorio.unifesp.br/handle/11600/28670

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