Clinical-histopathological correlation in a case of Coats' disease

Clinical-histopathological correlation in a case of Coats' disease

Autor Fernandes, Bruno F. Autor UNIFESP Google Scholar
Odashiro, Alexandre N. Autor UNIFESP Google Scholar
Maloney, Shawn Google Scholar
Zajdenweber, Moyses E. Google Scholar
Lopes, Andressa G. Google Scholar
Burnier, Miguel N. Autor UNIFESP Google Scholar
Instituição McGill Univ
Henry C Witelson Ocular Pathol Lab
Universidade Federal de São Paulo (UNIFESP)
Hosp Servidores Estado
Resumo Background: Coats' disease is a non-hereditary ocular disease, with no systemic manifestation, first described by Coats in 1908. It occurs more commonly in children and has a clear male predominance. Most patients present clinically with unilateral decreased vision, strabismus or leukocoria. the most important differential diagnosis is unilateral retinoblastoma, which occurs in the same age group and has some overlapping clinical manifestations.Case presentation: A 4 year-old girl presented with a blind and painful right eye. Ocular examination revealed neovascular glaucoma, cataract and posterior synechiae. Although viewing of the fundus was impossible, computed tomography disclosed total exsudative retinal detachment in the affected eye. the eye was enucleated and subsequent histopathological evaluation confirmed the diagnosis of Coats' disease.Conclusion: General pathologists usually do not have the opportunity to receive and study specimens from patients with Coats' disease. Coats' disease is one of the most important differential diagnoses of retinoblastoma. Therefore, It is crucial for the pathologist to be familiar with the histopathological features of the former, and distinguish it from the latter.
Idioma Inglês
Data 2006-01-01
Publicado em Diagnostic Pathology. London: Biomed Central Ltd, v. 1, 4 p., 2006.
ISSN 1746-1596 (Sherpa/Romeo, fator de impacto)
Editor Biomed Central Ltd
Extensão 4
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000205613100024

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