High degree of discordance between three-dimensional and two-dimensional lumbar spine bone mineral density in Turner's syndrome

High degree of discordance between three-dimensional and two-dimensional lumbar spine bone mineral density in Turner's syndrome

Autor Lage, A. Z. Google Scholar
Brandao, C. A. Google Scholar
Mendes, JRT Google Scholar
Huayllas, M. K. Google Scholar
Liberman, B. Google Scholar
Mendonca, B. B. Google Scholar
Costa, EMF Google Scholar
Verreschi, I. T. Google Scholar
Lazaretti-Castro, M. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Brigadeiro HOsp
Universidade de São Paulo (USP)
Resumo Low bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) has been described in Turner's syndrome (TS). One of the error factors of DXA is short stature, a common finding in TS patients. Aimed to evaluate the influence of a low stature on BMD. we compared the two-dimensional (2D) or conventional BMD (cBMD) with three-dimensional (3D) or volumetric BMD (vBMD) in 62 females (10 to 48 yr old) with TS diagnosis in a case control study. They were compared to 102 normal females (7 to 45 yr old) grouped by age-ranges. All patients were subjected to a lumbar spine densitometry by DXA in the PA and lateral projections, obtained the cBMD and vBMD and calculated for the apparent BMD (appBMD). in TS, the mean of Z-score for cBMD was significantly lower than that for vBMD and for appBMD (-2.31 +/- 1.42; -0.64 +/- 1.55; and -1.72 +/- 1.5; respectively). Most of the patients (93.8%) had a Z-score <-1 for cBMD, whereas the majority (58.1%) had a Z-score <-1 for vBMD. Concluding, the cBMD underestimates the bone mass of the lumbar spine in patients with TS inducing to false diagnoses of bone fragility. Volumetric BMD approached the bone mass of control patients, while appBMD just partially do that.
Palavra-chave Turner's syndrome
bone mineral density (BMD)
volumetric bone density (VBD)
Idioma Inglês
Data de publicação 2005-12-01
Publicado em Journal of Clinical Densitometry. Totowa: Humana Press Inc, v. 8, n. 4, p. 461-466, 2005.
ISSN 1094-6950 (Sherpa/Romeo, fator de impacto)
Publicador Humana Press Inc
Extensão 461-466
Fonte http://dx.doi.org/10.1385/JCD:8:4:461
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000233730700013
Endereço permanente http://repositorio.unifesp.br/handle/11600/28593

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta