Immunologic factors in human milk: the effects of gestational age and pasteurization

Immunologic factors in human milk: the effects of gestational age and pasteurization

Author Koenig, Alvaro Google Scholar
Diniz, Edna Maria de Albuquerque Google Scholar
Barbosa, Sonia FC Google Scholar
Vaz, Flavio Adolfo Costa Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Adolfo Lutz Inst
Abstract This study compared concentrations of total protein, lysozyme, and immuno-lobulins (IgA, IgG, IgM) in samples of colostrum (n = 101) obtained from mothers of infants < 32 weeks, 32 to 366/7, weeks, and >= 37 weeks gestational age, both before and after pasteurization. Total protein was measured by refraction index, lysozyme by the lysoplate method, and immunoglobulins through the radial immunodiffusion technique. the total protein concentration was greater in colostrum of the < 32 weeks and 32 to 366/7 weeks categories compared to full-term (P < .001), while concentrations of lysozyme and IgM were similar. IgA concentrations were higher in the < 32 weeks group compared to the full-term and similar to the 32 to 366/7 weeks group (P <.05). the IgG was higher in the < 32 weeks category compared to 32 to 366/7 weeks, and both were similar to the full-terin (P <.05). Pasteurization significantly decreased all of the factors analyzed.
Keywords human milk
colostrum
gestational age
IgA
IgG
IgM
lysozyme
pasteurization
Language English
Date 2005-11-01
Published in Journal of Human Lactation. Thousand Oaks: Sage Publications Inc, v. 21, n. 4, p. 439-443, 2005.
ISSN 0890-3344 (Sherpa/Romeo, impact factor)
Publisher Sage Publications Inc
Extent 439-443
Origin http://dx.doi.org/10.1177/0890334405280652
Access rights Closed access
Type Article
Web of Science ID WOS:000232830000007
URI http://repositorio.unifesp.br/handle/11600/28544

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