Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study

Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study

Autor Menezes, AMB Google Scholar
Perez-Padilla, R. Google Scholar
Jardim, JRB Google Scholar
Muino, A. Google Scholar
Lopez, M. V. Google Scholar
Valdivia, G. Google Scholar
Oca, M. M. de Google Scholar
Talamo, C. Google Scholar
Hallal, P. C. Google Scholar
Victoria, C. G. Google Scholar
PLATINO Team Google Scholar
Instituição Univ Fed Pelotas
Inst Nacl Enfermedades Resp
Universidade Federal de São Paulo (UNIFESP)
Univ Republica
Pontificia Univ Catolica Chile
Cent Univ Venezuela
Resumo Background Both the prevalence and mortality attributable to chronic obstructive pulmonary disease (COPD) seem to be increasing in low-income and middle-income countries, but few data are available. the aim of the PLATINO study, launched in 2002, was to describe the epidemiology of COPD in five major Latin American cities: São Paulo (Brazil), Santiago (Chile), Mexico City (Mexico), Montevideo (Uruguay), and Caracas (Venezuela).Methods A two-stage sampling strategy was used in the five areas to obtain probability samples of adults aged 40 years or older. These individuals were invited to answer a questionnaire and undergo anthropometry, followed by prebronchodilator and postbronchodilator spirometry. We defined COPD as a ratio less than 0.7 of postbronchodilator forced expiratory volume in the first second over forced vital capacity.Findings Complete information, including spirometry, was obtained from 963 people in São Paulo, 1173 in Santiago, 1000 in Mexico City, 885 in Montevideo, and 1294 in Caracas. Crude rates of COPD ranged from 7.8% (78 of 1000; 95% CI 5.9-9.7) in Mexico City to 19.7% (174 of 885; 17.2-22.2) in Montevideo. After adjustment for key risk factors, the prevalence of COPD in Mexico City remained significantly lower than that in other cities.Interpretation These results suggest that COPD is a greater health problem in Latin America than previously realised. Altitude may explain part of the difference in prevalence. Given the high rates of tobacco use in the region, increasing public awareness of the burden of COPD is important.
Idioma Inglês
Data 2005-11-01
Publicado em Lancet. London: Lancet Ltd, v. 366, n. 9500, p. 1875-1881, 2005.
ISSN 0140-6736 (Sherpa/Romeo, fator de impacto)
Editor Lancet Ltd
Extensão 1875-1881
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000233643200026

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