Pregnancy outcome for Rh-alloimmunized women

Pregnancy outcome for Rh-alloimmunized women

Autor Nardozza, LMM Google Scholar
Camano, L. Google Scholar
Moron, A. F. Google Scholar
Pares, DBD Google Scholar
Chinen, P. A. Google Scholar
Torloni, M. R. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: To compare perinatal results of Rh-alloimmunized pregnancies managed with spectrophotometric amniotic fluid analysis or fetal middle cerebral artery Doppler ultrasonographic velocimetry. Method: A descriptive observational study involving 291 consecutive Rh-negative pregnancies. Group I consisted of 74 isoimmunized women managed with amniotic fluid spectrophotometry; group 2 of 25 isoimmunized women managed with Doppler ultrasonography; and group 3 of 192 nonimmunized Rh-negative women. the variables analyzed were need for intrauterine or neonatal transfusion, mode and time of delivery, birth weight, neonatal hematocrit, and perinatal mortality. Results: Need for intrauterine transfusion, birth weight, prematurity, rate of cesarean section, and perinatal mortality were similar in groups 1 and 2. Neonatal hematocrit was significantly lower and the need for neonatal transfusion was significantly higher when spectrophotometry rather than Doppler ultrasonographic velocimetry was used. Conclusion: Fetuses managed with Doppler ultrasonographic velocimetry had a higher hematocrit at birth and a lesser need for neonatal transfusion, suggesting that this noninvasive method of monitoring fetal anemia is a better choice. (c) 2005 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Assunto red blood cell isoimmunization
fetal anemia
middle cerebral artery
Doppler ultrasonographic velocimetry
isoantibodies
fetal erythroblastosis
Idioma Inglês
Data 2005-08-01
Publicado em International Journal of Gynecology & Obstetrics. Clare: Elsevier B.V., v. 90, n. 2, p. 103-106, 2005.
ISSN 0020-7292 (Sherpa/Romeo, fator de impacto)
Editor Elsevier B.V.
Extensão 103-106
Fonte http://dx.doi.org/10.1016/j.ijgo.2005.04.007
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000231188000003
URI http://repositorio.unifesp.br/handle/11600/28403

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