Risk factors for asthma and atopy

Risk factors for asthma and atopy

Autor Arruda, L. K. Google Scholar
Sole, D. Google Scholar
Baena-Cagnani, C. E. Google Scholar
Naspitz, C. K. Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Catholic Univ Cordoba
Resumo Purpose of review the aim of this article is to provide information on risk factors associated with the development of atopy and asthma in childhood.Recent findings Several gene polymorphisms have been associated with susceptibility to asthma and allergy; complex gene-environmental interactions, however, appear to play a key role in the development of the disease. Early life sensitization to aeroallergens, presence of atopic dermatitis or allergic rhinitis, maternal smoking during pregnancy and children's environmental exposure to tobacco smoke, lower respiratory tract infections with respiratory syncytial virus and potentially with other viruses including rhinovirus and metapneumovirus, exposure to air pollutants, several perinatal factors other than maternal smoking, are among factors associated with an increased risk for development of chronic asthma.Summary the prevalence of asthma and allergic diseases is increasing progressively. Those who are involved in the care of young children should be prepared to recognize risk factors for development of these diseases and to appreciate the role of gene-environment interactions. Preventive measures established at an early age may modify the natural history of asthma and other allergic diseases.
Palavra-chave allergen sensitization
asthma
gene-environment interactions
respiratory viral infections
risk factors for asthma
Idioma Inglês
Data de publicação 2005-04-01
Publicado em Current Opinion in Allergy and Clinical Immunology. Philadelphia: Lippincott Williams & Wilkins, v. 5, n. 2, p. 153-159, 2005.
ISSN 1528-4050 (Sherpa/Romeo, fator de impacto)
Publicador Lippincott Williams & Wilkins
Extensão 153-159
Fonte http://dx.doi.org/10.1097/01.all.0000162308.89857.6c
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:000232293000008
Endereço permanente http://repositorio.unifesp.br/handle/11600/28235

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