Chronic myeloid leukemia following kidney transplantation

Chronic myeloid leukemia following kidney transplantation

Autor Pelloso, LAF Google Scholar
Campos, MGV de Google Scholar
Nascimento, M. Google Scholar
Silva, MRR Google Scholar
Pestana, JOM Google Scholar
Chauffaille, MDLF Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Immunosuppressed renal recipients are at an increased risk of developing cancer. Leukemias are less frequent than other hematopoietic tumours and development of CML after immunosuppression is rare. We describe a 37-year-old male who presented with left-shifted leukocytosis, hypercellular bone marrow 32 months after the kidney transplant. G-banding karyotype revealed 46,XY,t(9;22)(q34;q11) and the diagnosis of chronic myeloid leukemia was made. This is the 13th case of CML after kidney transplant reported. Whether this CML appeared as a random phenomenon or chemically induced is a matter of debate. Some individuals might have an increased susceptibility to the effects of azathioprine. (C) 2004 Elsevier B.V. All rights reserved.
Palavra-chave chronic myeloid leukemia
chemically induced leukemia
kidney transplantation
immunossupressive drugs
immunossupression
azathioprine
Idioma Inglês
Data de publicação 2005-03-01
Publicado em Leukemia Research. Oxford: Pergamon-Elsevier B.V., v. 29, n. 3, p. 353-355, 2005.
ISSN 0145-2126 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 353-355
Fonte http://dx.doi.org/10.1016/j.leukres.2004.07.008
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000226957600016
Endereço permanente http://repositorio.unifesp.br/handle/11600/28182

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