First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil

First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil

Autor Lincopan, Nilton Google Scholar
McCulloch, John Anthony Google Scholar
Reinert, Cristina Google Scholar
Cassettari, Valeria C. Google Scholar
Gales, Ana C Autor UNIFESP Google Scholar
Mamizuka, Elsa M. Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
Resumo A multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. the isolate presented an MIC of imipenem of 128 mug/ml, and the production of a metallo-beta-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of a metalloenzyme (IMP-1) -producing K. pneumoniae clinical strain in Latin America. the gene responsible for this phenotype was found to be bla(IMP-1), carried in a class 1 integron.
Idioma Inglês
Data de publicação 2005-01-01
Publicado em Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 43, n. 1, p. 516-519, 2005.
ISSN 0095-1137 (Sherpa/Romeo, fator de impacto)
Publicador Amer Soc Microbiology
Extensão 516-519
Fonte http://dx.doi.org/10.1128/JCM.43.1.516-519.2005
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000226380400089
Endereço permanente http://repositorio.unifesp.br/handle/11600/28064

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