Perinatal or early-postnatal cytomegalovirus infection in preterm infants under 34 weeks gestation born to CMV-seropositive mothers within a high-seroprevalence population

Perinatal or early-postnatal cytomegalovirus infection in preterm infants under 34 weeks gestation born to CMV-seropositive mothers within a high-seroprevalence population

Autor Mussi-Pinhata, M. M. Google Scholar
Yamamoto, A. Y. Google Scholar
Rego, MAD Google Scholar
Pinto, PCG Google Scholar
Da Motta, MSF Google Scholar
Calixto, C. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo In a prospective study, we evaluated the frequency, correlates, and clinical significance of perinatal or early-postnatal cytomegalovirus (CMV) infection in <34-week-gestation infants (n = 95) born to CMV-seropositive mothers. None had congenital CMV infection. Overall, 21 (22.1%; 95% CI = 14.2-31.8) infants were found to be infected; 10 excreted CMV at <60 days, and 11 had later excretion. Blood transfusion, birth weight, and vaginal delivery were not associated factors. Receiving natural breast milk within the first 30 days (OR = 4.5, P=.02) or for >30 days (OR = 7.9, P<.01) was associated with infection. Only one (4.8%) of the infected infants was symptomatic. for <34-week-gestation infants, frequency of perinatal and early-postnatal CMV infection is high. Early or prolonged exposure to breast milk is an associated factor. However, most infections are asymptomatic, indicating that CMV infection in preterm infants within such a population is a serious problem infrequently.
Idioma Inglês
Data de publicação 2004-11-01
Publicado em Journal of Pediatrics. New York: Mosby-Elsevier, v. 145, n. 5, p. 685-688, 2004.
ISSN 0022-3476 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 685-688
Fonte http://dx.doi.org/10.1016/j.jpeds.2004.07.025
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000225086800028
Endereço permanente http://repositorio.unifesp.br/handle/11600/28007

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