Inhibitors in haemophilia: clinical aspects

Inhibitors in haemophilia: clinical aspects

Autor DiMichele, D. Google Scholar
Rivard, G. Google Scholar
Hay, C. Google Scholar
Antunes, S. Google Scholar
Instituição Cornell Univ
St Justine Hosp
Manchester Royal Infirm
Universidade Federal de São Paulo (UNIFESP)
Resumo Inhibitor development continues to be a severe complication worldwide of haemophilia therapy. Given the difficulties associated with the treatment of inhibitors in both the developed and the developing world, prediction and prevention of inhibitors following exposure to factor VIII or IX in the young child has become a management priority. Two different clinical approaches to minimizing or delaying inhibitor development are highlighted in this manuscript. Challenges in the therapy of existing inhibitors persist. However, the nature of the issues faced by physicians in the developed and developing worlds vary considerably. Both are discussed in this manuscript by representatives of both worlds, who face these challenges on a daily basis.
Palavra-chave immune tolerance
inhibitor prevention
inhibitor risk factors
inhibitor therapy
Idioma Inglês
Data de publicação 2004-10-01
Publicado em Haemophilia. Oxford: Blackwell Publishing Ltd, v. 10, p. 140-145, 2004.
ISSN 1351-8216 (Sherpa/Romeo, fator de impacto)
Publicador Blackwell Publishing Ltd
Extensão 140-145
Fonte http://dx.doi.org/10.1111/j.1365-2516.2004.00993.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000226143400024
Endereço permanente http://repositorio.unifesp.br/handle/11600/27977

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