Levodopa effect upon functional balance of Parkinson's disease patients

Levodopa effect upon functional balance of Parkinson's disease patients

Autor Nova, I. C. Google Scholar
Perracini, M. R. Google Scholar
Ferraz, H. B. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective. the aim of this study was to evaluate functional balance in PD patients taking levodopa during their 'on' and 'off' phases.Design. We evaluated 23 PD patients who were manifesting fluctuations of levodopa effect. All patients were assessed by Hoehn-Yahr, UPDRS-III and Schwab-England rating scales and by the Berg functional balance scale during a practically defined 'off' (at least after 12 h the last levodopa intake) and 'on' (the mobile state induced by the drug) phases.Results. Mean scores obtained for all scales showed improvements during the 'on' phase of levodopa and all of the comparisons were statistically significant. Mean scores of Berg scale moved from 31.7 during the 'off' phase to 42.7 during the 'on' phase. Mean UPDRS 'off' and 'on' scores were 50.6 and 32.0, respectively.Conclusion. We conclude that Berg functional balance scale is able to detect changes in balance and that levodopa can modify the postural instability of PD patients. (C) 2004 Elsevier B.V. All rights reserved.
Palavra-chave Parkinson's disease
levodopa
postural instability
balance berg functional balance scale
Idioma Inglês
Data de publicação 2004-10-01
Publicado em Parkinsonism & Related Disorders. Oxford: Elsevier B.V., v. 10, n. 7, p. 411-415, 2004.
ISSN 1353-8020 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 411-415
Fonte http://dx.doi.org/10.1016/j.parkreldis.2004.04.004
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000224607900004
Endereço permanente http://repositorio.unifesp.br/handle/11600/27966

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