Prognosis of ARF in hospitalized elderly patients

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dc.contributor.author Sesso, R.
dc.contributor.author Roque, A.
dc.contributor.author Vicioso, B.
dc.contributor.author Stella, S.
dc.date.accessioned 2016-01-24T12:37:21Z
dc.date.available 2016-01-24T12:37:21Z
dc.date.issued 2004-09-01
dc.identifier http://dx.doi.org/10.1053/j.ajkd.2004.05.022
dc.identifier.citation American Journal of Kidney Diseases. Philadelphia: W B Saunders Co, v. 44, n. 3, p. 410-419, 2004.
dc.identifier.issn 0272-6386
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/27924
dc.description.abstract Background: Differentiation between hospital-acquired acute renal failure (ARF) and community-acquired ARF may have epidemiological implications that lead to different prognoses in hospitalized patients. Such a comparison has not yet been made among elderly individuals. Methods: We performed a 3-year prospective study in a tertiary referral hospital of 325 patients aged 60 years or older who presented with ARF. Patients were divided into 2 groups; those with hospital-acquired ARF (n=154) and community-acquired ARF (n=171), and were followed up in relation to mortality. Multiple logistic regression was used in the analysis. Results: the overall mortality rate in this elderly population was 54%; 59% for the group with hospital-acquired ARF and 41% for the group with community-acquired ARF (P<0.001). Groups differed (P<0.01) in relation to cause of ARF, preexisting diseases, organ failure, sepsis, and performance of dialysis, among other factors. the adjusted mortality risk for the group with hospital-acquired ARF was 2.23 times greater than for the group with community-acquired ARF (95% confidence interval [CI], 1.21 to 4.08). in the group with hospital-acquired ARF, factors associated with mortality were neurological failure (odds ratio [OR], 2.97; 95% CI, 1.17 to 7.60), hematologic failure (OR, 4.30; 95% CI, 1.63 to 11.34), and oliguria (OR, 12.14; 95% CI, 4.62 to 31.87). in the group with community-acquired ARF, significant factors were neoplasia, cardiac disease, hepatic disease, cardiovascular failure, oliguria, and sepsis. Conclusion Differentiation between hospital-acquired ARF and community-acquired ARF is important in determining the prognosis of ARF in the elderly. Mortality risk factors are different in these 2 groups, and knowledge of their characteristics may allow better management of such patients. en
dc.format.extent 410-419
dc.language.iso eng
dc.publisher W B Saunders Co
dc.relation.ispartof American Journal of Kidney Diseases
dc.rights Acesso restrito
dc.subject acute renal failure (ARF) en
dc.subject elderly en
dc.subject hospital acquired en
dc.subject community acquired en
dc.subject mortality en
dc.title Prognosis of ARF in hospitalized elderly patients en
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Univ Texas
dc.description.affiliation UNIFESP, Escola Paulista Med, Div Nephrol, BR-04023900 São Paulo, Brazil
dc.description.affiliation Univ Texas, SW Med Ctr, Dept Med, Dallas, TX USA
dc.description.affiliationUnifesp UNIFESP, Escola Paulista Med, Div Nephrol, BR-04023900 São Paulo, Brazil
dc.identifier.doi 10.1053/j.ajkd.2004.05.022
dc.description.source Web of Science
dc.identifier.wos WOS:000223648500003



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