Canine paracoccidioidomycosis

Canine paracoccidioidomycosis

Autor Ricci, G. Google Scholar
Mota, F. T. Google Scholar
Wakamatsu, A. Google Scholar
Serafim, R. C. Google Scholar
Borra, R. C. Google Scholar
Franco, M. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Pathol Lab
Adolfo Lutz Inst
Resumo Paracoccidioidomycosis (PCM) is a severe disease caused by the dimorphic fungus Paracoccidioides brasiliensis, which is characterized by granulomatous pulmonary and systemic lesions, affecting mainly men between 20 and 60 years of age. Reports of PCM disease in animals are rare, but the disease has been described in armadillos. On the other hand, PCM infection of domestic and wild animals detected by serological or cutaneous tests in the absence of apparent disease has been frequently reported. We present here the case of a female adult Doberman that developed cervical lymphadenomegaly. Histopathological examination of a cervical biopsy specimen revealed active PCM, with an epithelioid, granulomatous inflammation containing numerous yeast-like, multiple budding fungal forms. the diagnosis of PCM was confirmed by immunohistochemistry using a specific antibody anti-gp43 and by nested PCR using primers for the amplification of the gp43 gene region. This is the first report of PCM disease occurring in a dog, an animal that has been shown to play an important role in the natural history of North American blastomycosis.
Palavra-chave animals
fungus
paracoccidioidomycosis
PCR
Idioma Inglês
Data de publicação 2004-08-01
Publicado em Medical Mycology. Abingdon: Taylor & Francis Ltd, v. 42, n. 4, p. 379-383, 2004.
ISSN 1369-3786 (Sherpa/Romeo, fator de impacto)
Publicador Taylor & Francis Ltd
Extensão 379-383
Fonte http://dx.doi.org/10.1080/1369378032000141417
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000223826600013
Endereço permanente http://repositorio.unifesp.br/handle/11600/27864

Exibir registro completo




Arquivo

Arquivo Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item está nas seguintes coleções

Buscar


Navegar

Minha conta