The long-term results of keratoplasty in eyes with a glaucoma drainage device

The long-term results of keratoplasty in eyes with a glaucoma drainage device

Autor Alvarenga, L. S. Google Scholar
Mannis, M. J. Google Scholar
Brandt, J. D. Google Scholar
Lee, W. B. Google Scholar
Schwab, I. R. Google Scholar
Lim, M. C. Google Scholar
Instituição Univ Calif Davis
Universidade Federal de São Paulo (UNIFESP)
Resumo PURPOSE: To study the outcome of penetrating keratoplasty (PK) in eyes with a glaucoma drainage device (GDD).DESIGN: Retrospective case-controlled study.METHODS: We reviewed all patients who underwent PK from December 1986 to September 2002 at the University of California, Davis (n = 1,974). We identified 33 patients (40 grafts) who were treated with a GDD and followed up for 6 months or more after PK. Graft survival and glaucoma control were compared with grafts in patients without glaucoma (n = 40) and patients with medically controlled glaucoma (n = 17). Kaplan-Meier survival analysis, log rank test, repeated-measures analysis of variance (ANOVA), Fisher exact test, and chi(2) were used in group comparisons. Multivariate analysis was performed using the Cox proportional hazards model.RESULTS: the percentages of clear grafts in the glaucoma drainage device group were 58.5% and 25.8% at 1 and 2 years, respectively. At these time points, glaucoma was controlled in 74.0% and 63.1% of the eyes, respectively. Both medically controlled glaucoma patients and nonglaucomatous patients had higher graft survival percentages at comparable time points. the presence of a GDD was an important factor influencing graft survival (Hazard ratio = 6.8).CONCLUSION: A GDD implant is an independent risk factor for graft failure. Although these devices are effective in controlling intraocular pressure (IOP) in the majority of eyes in the presence of PK, corneal graft clarity is often compromised. (C) 2004 by Elsevier Inc. All rights reserved.
Idioma Inglês
Data de publicação 2004-08-01
Publicado em American Journal of Ophthalmology. New York: Elsevier B.V., v. 138, n. 2, p. 200-205, 2004.
ISSN 0002-9394 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 200-205
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000223186100004
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