Long-term effects of early malnutrition on body weight regulation

Long-term effects of early malnutrition on body weight regulation

Autor Sawaya, Ana Lydia Autor UNIFESP Google Scholar
Martins, Paula A. Autor UNIFESP Google Scholar
Grillo, Luciane P. Google Scholar
Florencio, Telma T. Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Univ Vale Itajai
Univ Fed Alagoas
Resumo Malnutrition is still highly prevalent in developing countries. Studies have shown an increase in the number of obese individuals in very poor urban communities. This review shows a co-existence between malnutrition and obesity in households of slums in Brazil and a higher prevalence of stunted/overweight or obese individuals (30%) in comparison with stunted/underweight (16%). These conditions are associated with important metabolic changes. Results from stunted children showed higher susceptibility to the effects of higher fats diets, lower fat oxidation, higher central fat, and higher body fat gain. A model to explain how early malnutrition alters energy balance in adults is outlined. in the presence of a relative food intake insufficiency, a higher corti-sol:insulin ratio, associated with lower levels of IGF-1 will lead to lower muscle gain and linear growth, impaired lypolysis and fat oxidation. When these hormonal changes are combined with a higher fat/carbohydrate and/or marked decreased in physical activity, obesity with short stature will occur. Key words: malnutrition, stunting, obesity, body weight regulation (c) 2004 International Life Sciences Institute.
Palavra-chave malnutrition
body weight regulation
Idioma Inglês
Data de publicação 2004-07-01
Publicado em Nutrition Reviews. Washington: Int Life Sciences Inst North America, v. 62, n. 7, p. S127-S133, 2004.
ISSN 0029-6643 (Sherpa/Romeo, fator de impacto)
Publicador Int Life Sciences Inst North America
Extensão S127-S133
Fonte http://onlinelibrary.wiley.com/doi/10.1111/j.1753-4887.2004.tb00082.x/abstract
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000227612100010
Endereço permanente http://repositorio.unifesp.br/handle/11600/27812

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