Simultaneous pancreas-kidney transplantation: Infectious complications and microbiological aspects

Simultaneous pancreas-kidney transplantation: Infectious complications and microbiological aspects

Autor Linhares, M. M. Google Scholar
Gonzalez, A. M. Google Scholar
Trivino, T. Google Scholar
Barbosa, MMLS Google Scholar
Schraibman, V Google Scholar
Melaragno, C. Google Scholar
Moura, RMAM Google Scholar
Silva, MHG Google Scholar
Sa, JR Google Scholar
Aguiar, W. F. Google Scholar
Rangel, E. B. Google Scholar
Serra, C. B. Google Scholar
Succi, T. Google Scholar
Pestana, JOM Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Resumo Objective: the purpose of this study was to describe the clinical and microbiological characteristics of the infectious complications among simultaneous pancreas-kidney transplantations (SPKT).Materials and methods. Among the first 45 SPKT the mean age was 34 years (range, 21 to 49) and the mean duration of follow-up 13 months (range, 2 to 27 months).Results: Twenty-three patients (51%) presented at least one to three episodes (1.7 mean) of infectious complications that needed hospitalization. the etiology of the infections included 71% bacterial (44% gram-negative rods and 27% gram-positive cocci), 16% viral (12% from CMV and 4% from Herpes sp) and 13% fungal (8% by Candida sp and 4% by others fungus). Wound and urinary infections were most frequent, occurring in 22% and 28% of the patients, respectively. All patients who were submitted to vesical drainage developed infections in contrast a rate of only 44% among patients undergoing enteric drainage.Conclusion: Infectious complications are the main cause of morbidity and mortality following simultaneous pancreas-kidney transplantation, especially with vesical drainage. the use of enteric drainage combined with administration of broad spectrum prophylactic antibiotics is recommended.
Idioma Inglês
Data 2004-05-01
Publicado em Transplantation Proceedings. New York: Elsevier B.V., v. 36, n. 4, p. 980-981, 2004.
ISSN 0041-1345 (Sherpa/Romeo, fator de impacto)
Editor Elsevier B.V.
Extensão 980-981
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000222063800065

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