Microchimerism does not correlate with survival of murine cardiac allografts

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dc.contributor.author Moraes, L. V. de
dc.contributor.author Bueno, V
dc.contributor.author Panajotopoulos, N.
dc.contributor.author Rizzo, L. V.
dc.date.accessioned 2016-01-24T12:37:09Z
dc.date.available 2016-01-24T12:37:09Z
dc.date.issued 2004-05-01
dc.identifier http://dx.doi.org/10.1016/j.transproceed.2004.03.053
dc.identifier.citation Transplantation Proceedings. New York: Elsevier B.V., v. 36, n. 4, p. 1021-1022, 2004.
dc.identifier.issn 0041-1345
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/27742
dc.description.abstract The development of microchimerism was evaluated at different time points after infusion of a mixed population of bone marrow and spleen cells from (BALB/c x C57B1/6)F1 mice in the presence or absence of a cardiac transplant. Microchimerism was observed in the spleen, bone marrow and thymus of transplanted BALB/c mice even after graft rejection. in the absence of transplantation, donor cells persisted especially in the thymus. the results show that despite augmentation of graft survival after donor cell infusion compared to nontreated controls, the development of microchimerism did not sustain cardiac semihistocompatible grafts. Moreover, the persistence of donor cells in the thymus in both situations suggests a role for this organ in the increased graft survival in our model. en
dc.format.extent 1021-1022
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Transplantation Proceedings
dc.rights Acesso restrito
dc.title Microchimerism does not correlate with survival of murine cardiac allografts en
dc.type Artigo
dc.rights.license http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Fdn Zerbini
dc.contributor.institution Brazilian Minist Sci & Technol
dc.description.affiliation Univ São Paulo, Inst Ciencias Biomed, Dept Immunol, BR-05508900 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Paulista Sch Med, Div Nephrol, São Paulo, Brazil
dc.description.affiliation Inst Heart, InCor, Transplantat Lab, São Paulo, Brazil
dc.description.affiliation Univ São Paulo, Sch Med, Div Clin Immunol & Allergy, São Paulo, Brazil
dc.description.affiliation Fdn Zerbini, São Paulo, Brazil
dc.description.affiliation Brazilian Minist Sci & Technol, Inst Invest Immunol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Paulista Sch Med, Div Nephrol, São Paulo, Brazil
dc.identifier.doi 10.1016/j.transproceed.2004.03.053
dc.description.source Web of Science
dc.identifier.wos WOS:000222063800080



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