Lipid profile in women over 35 years old using triphasic combined oral contraceptives

Lipid profile in women over 35 years old using triphasic combined oral contraceptives

Autor Aldrighi, J. M. Google Scholar
Petta, C. A. Google Scholar
Bahamondes, L. Google Scholar
Caetano, M. E. Google Scholar
Martinez, TRL Google Scholar
De Lima, G. R. Google Scholar
Instituição Universidade de São Paulo (USP)
Universidade Estadual de Campinas (UNICAMP)
Universidade Federal de São Paulo (UNIFESP)
Resumo Twenty-nine women aged 35 years old or more, using triphasic combined oral contraceptive (COC) were evaluated during six cycles for the following parameters: total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and its subfraction HDL2, triglycerides, apoproteins A and B, Castelli risk index I and II (cholesterol/HDL-C and LDL-C/HDL-C) and apoprotein ratio (apoprotein B/apoprotein A). the same laboratory measurements were done in a control group of 49 non-COC-user women. the results showed that there were no differences on most of the studied parameters between user and nonuser women. There was a significant reduction of HDL-C and LHD2-C, although within the normal range. in addition, it was observed a significant increment of triglycerides and apoprotein B at 6 months of follow-up only in user group (p < 0.05), although within the normal range. It is concluded that the use of levonorgestrel triphasic COC appeared to have no additional adverse impact when used by women aged over 35 years. Further studies are needed to obtain conclusive data. (C) 2004 Elsevier Inc. All rights reserved.
Palavra-chave oral contraceptives
cardiovascular risk
levonorgestrel
ethinylestradiol
Idioma Inglês
Data de publicação 2004-05-01
Publicado em Contraception. New York: Elsevier B.V., v. 69, n. 5, p. 395-399, 2004.
ISSN 0010-7824 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 395-399
Fonte http://dx.doi.org/10.1016/j.contraception.2004.01.005
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000221176000009
Endereço permanente http://repositorio.unifesp.br/handle/11600/27728

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