Heavier-than-air flying machines are impossible

Heavier-than-air flying machines are impossible

Autor Oliveira, Laerte Autor UNIFESP Google Scholar
Hulsen, T. Google Scholar
Hulsik, D. L. Google Scholar
Paiva, Antonio Cechelli de Mattos Autor UNIFESP Google Scholar
Vriend, Gerrit Google Scholar
Instituição KUN
Universidade Federal de São Paulo (UNIFESP)
Univ Utrecht
Resumo Many G protein-coupled receptor (GPCR) models have been built over the years. the release of the structure of bovine rhodopsin in August 2000 enabled us to analyze models built before that period to learn more about the models we build today. We conclude that the GPCR modelling field is riddled with 'common knowledge' similar to Lord Kelvin's remark in 1895 that heavier-than-air flying machines are impossible, and we summarize what we think are the (im)possibilities of modelling GPCRs using the coordinates of bovine rhodopsin as a template. Associated WWW pages: http://www.gpcr.org/ articles/2003_mod/. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
Palavra-chave GPCR
modelling
bovine rhodopsin
bacteriorhodopsin
superposition
alignment
Idioma Inglês
Data de publicação 2004-04-30
Publicado em Febs Letters. Amsterdam: Elsevier B.V., v. 564, n. 3, p. 269-273, 2004.
ISSN 0014-5793 (Sherpa/Romeo, fator de impacto)
Publicador Elsevier B.V.
Extensão 269-273
Fonte http://dx.doi.org/10.1016/S0014-5793(04)00320-5
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000221170600012
Endereço permanente http://repositorio.unifesp.br/handle/11600/27712

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