Autor |
Mello, Marco Tulio de
![]() ![]() Esteves, A. M. ![]() Tufik, Sergio ![]() ![]() |
Instituição | Universidade Federal de São Paulo (UNIFESP) |
Resumo | Study design: Randomized controlled trial of physical exercise and dopaminergic agonist in persons with spinal cord injury and periodic leg movement (PLM).Objective: the objective of the present study was to compare the effectiveness of physical exercise and of a dopaminergic agonist in reducing the frequency of PLM.Setting: Centro de Estudos em Psicobiologia e Exercicio. Universidade Federal de São Paulo, Brazil.Methods: A total of 13 volunteers (mean age: 31.6 +/- 8.3 years) received L-DOPA ( 200 mg) and benserazide ( 50 mg) 1 h before sleeping time for 30 days and were then submitted to a physical exercise program on a manual bicycle ergometer for 45 days ( 3 times a week).Results: Both L-DOPA administration (35.11 - 19.87 PLM/h, P<0.03) and physical exercise (35.11 - 18.53 PLM/h, P<0.012) significantly reduced PLM; however, no significant difference was observed between the two types of treatment.Conclusions: the two types of treatment were found to be effective in the reduction of PLM; however, physical exercise is indicated as the first treatment approach, while dopaminergic agonists or other drugs should only be recommended for patients who do not respond to this type of treatment. |
Palavra-chave |
periodic limb movement (PLM)
physical exercise L-DOPA aerobic training spinal cord injury sleep disorders |
Idioma | Inglês |
Data de publicação | 2004-04-01 |
Publicado em | Spinal Cord. London: Nature Publishing Group, v. 42, n. 4, p. 218-221, 2004. |
ISSN | 1362-4393 (Sherpa/Romeo, fator de impacto) |
Publicador | Nature Publishing Group |
Extensão | 218-221 |
Fonte |
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Direito de acesso | Acesso aberto ![]() |
Tipo | Artigo |
Web of Science | WOS:000220586600003 |
Endereço permanente | http://repositorio.unifesp.br/handle/11600/27679 |
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