Are idiopathic and chagasic achalasia two different diseases?

Are idiopathic and chagasic achalasia two different diseases?

Author Herbella, FAM Google Scholar
Oliveira, DRCF Google Scholar
Del Grande, J. C. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Although Chagas' disease esophagopaty and idiopathic (primary) achalasia share several similarities, however, some differences between the two diseases have been noticed. To evaluate if treatment options and their results can be accepted universally, the authors review characteristics of both diseases in the international and Latin American literature. Neuronal denervation, sensitivity to gastrin, patient age, duration of symptoms, lower esophageal sphincter pressure, incidence of vigorous achalasia, and cancer risk are considered points of discrepancy between the maladies. Data with a high level of evidence base are scarce; however, differences between the diseases seem to exist, despite the fact that no influence on response to treatment was noticed.
Keywords achalasia
megaesophagus
Chagas' disease
esophagus
Language English
Date 2004-03-01
Published in Digestive Diseases and Sciences. New York: Kluwer Academic/plenum Publ, v. 49, n. 3, p. 353-360, 2004.
ISSN 0163-2116 (Sherpa/Romeo, impact factor)
Publisher Kluwer Academic/plenum Publ
Extent 353-360
Origin http://dx.doi.org/10.1023/B:DDAS.0000020486.71719.62
Access rights Closed access
Type Review
Web of Science ID WOS:000220339900001
URI http://repositorio.unifesp.br/handle/11600/27658

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