Clinical value of preoperative mechanical bowel cleansing in elective colorectal surgery: A systematic review

Clinical value of preoperative mechanical bowel cleansing in elective colorectal surgery: A systematic review

Autor Wille-Jorgensen, P. Google Scholar
Guenaga, K. F. Google Scholar
Castro, A. A. Google Scholar
Matos, D. Google Scholar
Instituição Univ Copenhagen
Universidade Federal de São Paulo (UNIFESP)
Resumo Purpose: This study was designed to establish scientific evidence for and clinical results of preoperative mechanical bowel cleansing before elective colorectal surgery. Methods: Systematic literature searches in electronic databases, conference proceedings, and hand searches of reference lists of previously retrieved literature without any language restrictions were used. Only randomized trials were included. A quality assessment of each retrieved trial was performed. Outcome measures were surgical infections, mortality, and anastomotic dehiscence. Meta-analyses of the selected trials were performed using the Peto odds ratio. Results: the results of each outcome were as follows. 1) Overall anastomotic leakage-six studies: 5.5 percent with cleansing compared with 2.9 percent without cleansing; odds ratio 1.94, 95 percent confidence interval: 1.09 to 3.43 (P=0.02). 2) Peritonitis-three studies: 5.1 percent with cleansing compared with 2.8 percent without cleansing; odds ratio 1.90, 95 percent confidence interval: 0.78 to 4.64 (not significant). 3) Wound infection-six studies: 7.4 percent with cleansing compared with 5.7 percent without cleansing; odds ratio 1.34, 95 percent confidence interval: 0.85 to 2.13 (not significant). Conclusions: There is no evidence in the literature for beneficial effects from the use of bowel cleansing before elective colorectal surgery. Cleansing seems to be associated with an increased risk of more anastomotic dehiscence. Further studies stratifying between rectal and colonic surgery are warranted.
Assunto colorectal
surgery
bowel preparation
preoperative
elective
Idioma Inglês
Data 2003-08-01
Publicado em Diseases of the Colon & Rectum. Philadelphia: Lippincott Williams & Wilkins, v. 46, n. 8, p. 1013-1018, 2003.
ISSN 0012-3706 (Sherpa/Romeo, fator de impacto)
Editor Lippincott Williams & Wilkins
Extensão 1013-1018
Fonte http://dx.doi.org/10.1097/01.DCR.0000080151.35300.20
Direito de acesso Acesso restrito
Tipo Resenha
Web of Science WOS:000184748900002
URI http://repositorio.unifesp.br/handle/11600/27360

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